This page highlights the top published articles in the field of cardiology, electrophysiology, and digital health.



31.01.2024: My January EP, AI, and Cardiology Selection:



Long-Term Outcomes of Resynchronization–Defibrillation for Heart Failure


Stroke risk in women with atrial fibrillation.


Arrhythmic Risk in Biventricular Pacing Compared with Left Bundle Branch Area Pacing: Results From the I-CLAS Study


Sex-Specific Outcomes of LBBAP Versus Biventricular Pacing: Results From I-CLAS


Outcomes of Upgrading to LBBP in CRT Nonresponders: A Prospective, Multicenter, Nonrandomized, Case-Control Study


In Vivo Base Editing of Scn5a Rescues Type 3 Long QT Syndrome in Mice


Update on Cardiovascular Implantable Electronic Device Infections and Their Prevention, Diagnosis, and Management: A Scientific Statement from the American Heart Association


2023 ACC/AHA/ACCP/HRS Guideline for the Diagnosis and Management of Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines


Sudden Cardiac Death in Young Athletes: JACC State-of-the-Art Review


Antithrombotic Therapy for Patients Undergoing Cardiac Electrophysiological and Interventional Procedures: JACC State-of-the-Art Review


Ablation for atrial fibrillation improves the outcomes in patients with heart failure with preserved ejection fraction.


Association of vectorcardiographic T-wave area with clinical and echocardiographic outcomes in cardiac resynchronization therapy


Redo procedures after sinus node sparing hybrid ablation for inappropriate sinus tachycardia/postural orthostatic sinus tachycardia.


Electrophysiological characteristics and ablation of ventricular arrhythmias originating from the intramural basal inferior septum.


Effects of Contact Force on Lesion Size During Pulsed Field Catheter Ablation: Histochemical Characterization of Ventricular Lesion Boundaries


Clinical Management of Brugada Syndrome: Commentary From the Experts


Triggers of Ventricular Fibrillation in Patients With Inferolateral J-Wave Syndrome


QRS Morphology and the Risk of Ventricular Tachyarrhythmia in Cardiac Resynchronization Therapy Recipients


Bilateral Cardiac Sympathetic Denervation for Refractory Multifocal Premature Ventricular Contractions in Patients With Nonischemic Cardiomyopathy


A novel automated peak frequency annotation algorithm for identifying deceleration zones and ventricular tachycardia ablation sites.


UltraSOUND-based characterization of ventricular tachycardia SCAR and arrhythmogenic substrate: The SOUNDSCAR study


How to perform cardioneuroablation for vasovagal syncope and functional bradycardia


Advances in understanding of cardiac sodium channel structure/function and their relation to disease pathogenesis and treatment




Impact of a clinician-to-clinician electronic consultation in heart failure patients with previous hospital admissions


Peripartum Cardiomyopathy


Treatment of severe symptomatic aortic valve stenosis using non-invasive ultrasound therapy: a cohort study


Dapagliflozin and Mode of Death in Heart Failure with Improved Ejection Fraction. A Post Hoc Analysis of the DELIVER Trial


Residual leaks following percutaneous left atrial appendage occlusion and outcomes: a meta-analysis.


Platelet biology and function: plaque erosion vs. rupture


2023 American Heart Association Focused Update on Adult Advanced Cardiovascular Life Support: An Update to the American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care


Cardiac Catheterization Laboratory Management of the Comatose Adult Patient with an Out-of-Hospital Cardiac Arrest: A Scientific Statement From the American Heart Association


Coronary Artery Calcification: Current Concepts and Clinical Implications


Resistance Exercise Training in Individuals With and Without Cardiovascular Disease: 2023 Update: A Scientific Statement From the American Heart Association


High-Sensitivity Cardiac Troponin I Enhances Preeclampsia Prediction Beyond Maternal Factors and the sFlt-1/PlGF Ratio


Critical Care Management of Patients After Cardiac Arrest: A Scientific Statement from the American Heart Association and Neurocritical Care Society


Lipoprotein(a) Is Markedly More Atherogenic Than LDL: An Apolipoprotein B-Based Genetic Analysis


Comparison of Direct Oral Anticoagulants vs Vitamin K Antagonists After Transcatheter Mitral Valve Replacement



Artificial Intelligence:


Artificial intelligence in detecting left atrial appendage thrombus by transthoracic echocardiography and clinical features: the Left Atrial Thrombus on Transesophageal Echocardiography (LATTEE) registry


Wearable Digital Health Technologies for Monitoring in Cardiovascular Medicine


Improving cardiovascular risk prediction through machine learning modelling of irregularly repeated electronic health records 


Machine learning-derived cycle length variability metrics predict spontaneously terminating ventricular tachycardia in implantable cardioverter defibrillator recipients


Automatic triage of twelve-lead electrocardiograms using deep convolutional neural networks: a first implementation study


02.01.2024: My December Electrophysiology and Cardiology Selection:


Inhibition of the KCa2 potassium channel in atrial fibrillation: a randomized phase 2 trial


ECG deep learning for predicting post-procedural mortality: a model development and validation study


Prevalence and incidence of diastolic dysfunction in atrial fibrillation: clinical implications


Acquired risk factors and incident atrial fibrillation according to age and genetic predisposition


Sinus rhythm QRS morphology reflects right ventricular activation and anatomical ventricular tachycardia isthmus conduction in repaired tetralogy of Fallot


Association of epicardial and intramyocardial fat with ventricular arrhythmias


Diagnostic pitfalls in patients referred for arrhythmogenic right ventricular cardiomyopathy


Effects of Synchronizing Foot Strike and Cardiac Phase on Exercise Hemodynamics in Patients with Cardiac Resynchronization Therapy: A Within-Subjects Pilot Study to Fine-Tune Cardio-Locomotor Coupling for Heart Failure


Association of LP(a) Levels with Myocardial Fibrosis in the Multi-Ethnic Study of Atherosclerosis


Assessing left atrial intramyocardial fat infiltration from computerized tomography angiography in patients with atrial fibrillation


Genetic Atrial Cardiomyopathies: Common Features, Specific Differences, and Broader Relevance to Understanding Atrial Cardiomyopathy


Vascular Endothelial Barrier Protection Prevents Atrial Fibrillation by Preserving Cardiac Nanostructure


The Prevalence and Characteristics of Arrhythmic Mitral Valve Prolapse in Patients with Unexplained Cardiac Arrest


Utility of Very High-Output Pacing to Identify VT Circuits in Patients Manifesting Traditionally Inexcitable Scar


Posterior Wall Isolation Improves Outcomes for Persistent AF with Rapid Posterior Wall Activity: CAPLA Sub-study


ECG characteristics of “true” left bundle branch block: Insights from transcatheter aortic valve–related LBBB and His-Purkinje conduction system pacing–correctable LBBB


Association between nighttime heart rate and cardiovascular mortality in patients with implantable cardioverter-defibrillator: A cohort study


Restoration of calcium release synchrony: A novel target for heart failure and ventricular arrhythmia



Restrictive or Liberal Transfusion Strategy in Myocardial Infarction and Anemia


A Placebo-Controlled Trial of Percutaneous Coronary Intervention for Stable Angina


Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes


Metabolic mechanisms in physiological and pathological cardiac hypertrophy: new paradigms and challenges


Daily low-dose aspirin and incident type 2 diabetes in community-dwelling healthy older adults: a post-hoc analysis of efficacy and safety in the ASPREE randomized placebo-controlled trial


Variants at the Interleukin 1 Gene Locus and Pericarditis


Mechanisms of enhanced renal and hepatic erythropoietin synthesis by sodium–glucose cotransporter 2 inhibitors


Safety and Tolerability of Inclisiran for Treatment of Hypercholesterolemia in 7 Clinical Trials


Role of Advanced Practice Providers in the Cardiac Intensive Care Unit Team


Comparison of Intravascular Imaging, Functional, or Angiographically Guided Coronary Intervention


13.09.2023 My August Electrophysiology and Cardiology Selection:


Fatal Cardiac Arrhythmias during Electronic Gaming in Patients with Genetically Mediated Heart Diseases


Return-to-Play for Elite Athletes with Genetic Heart Diseases Predisposing to Sudden Cardiac Death


Risk of Arrhythmic Death in Patients with Non-ischemic Cardiomyopathy: JACC Review


Autoimmune Atrial Fibrillation


Ventricular Electrograms Duration Map to Detect Ventricular Arrhythmia Substrate: the VEDUM Project Study


Dronedarone Versus Sotalol in Antiarrhythmic Drug–Naive Veterans With Atrial Fibrillation


Lipomatous Metaplasia Facilitates Slow Conduction in Critical Ventricular Tachycardia Corridors within postinfarct Myocardium


Conduction Velocity Dispersion Predicts Postinfarct Ventricular Tachycardia Circuit Sites and Associates With Lipomatous Metaplasia


Reappraisal and New Observations on Idiopathic Ventricular Arrhythmias Ablated From the Noncoronary Aortic Sinus


Mitral Annular Substrate and Ventricular Arrhythmias in Arrhythmogenic Mitral Valve Prolapse with Mitral Annular Disjunction


Arrhythmic Mitral Valve Prolapse With Only Mild or Moderate Mitral Regurgitation: Characterization of Myocardial Substrate


Long-Term Outcome of Cardiac Denervation Procedures: The Anatomically Guided Septal Approach


Pulmonary Artery Denervation Inhibits Left Stellate Ganglion Stimulation-Induced Ventricular Arrhythmias Originating From the RVOT


A Novel ECG-Based Deep Learning Algorithm to Predict Cardiomyopathy in Patients with Premature Ventricular Complexes


Epicardial Roof-Dependent Macro–Re-Entrant Tachycardia after Ablation of Atrial Fibrillation: Electrophysiological Characteristics and Ablation


Utility and Limitations of Ablation Index for Guiding Therapy in Ventricular Myocardium


Substrate Imaging Before Catheter Ablation of Ventricular Tachycardia: Risk Prediction for Acute Hemodynamic Decompensation


Association of Sinus Wavefront Activation and Ventricular Extrastimuli Mapping with Ventricular Tachycardia Re-Entrant Circuits


Catheter ablation of ventricular premature depolarizations originating from the mid interventricular septum: Significance of electrocardiographic morphology for predicting origin


Improved outcomes of conduction system pacing in heart failure with reduced ejection fraction: A systematic review and meta-analysis


Polygenic risk scores are associated with atrial electrophysiologic substrate abnormalities and outcomes after atrial fibrillation catheter ablation



Artificial intelligence-based model to classify cardiac functions from chest radiographs: a multi-institutional, retrospective model development and validation study


Cardiac Remodeling in Subclinical Hypertrophic Cardiomyopathy: The VANISH Trial


Modification of the GRACE Risk Score for Risk Prediction in Patients with Acute Coronary Syndromes


Novel mechanisms and therapeutic targets in atherosclerosis: inflammation and beyond


Coronary steal: how many thieves are out there?


Novel therapy for ischemia with no obstructive coronary arteries


Stroke in patients with heart failure and reduced or preserved ejection fraction


Personalized antiplatelet therapies for coronary artery disease: what the future holds


Considerations on the Management of Acute Postoperative Ischemia after Cardiac Surgery: A Scientific Statement from the American Heart Association


Right Ventricular Function and Pulmonary Coupling in Patients with Heart Failure and Preserved Ejection Fraction


Management of Worsening Heart Failure with Reduced Ejection Fraction


25.08.2023: My July Electrophysiology and Cardiology Selection:



Use, misuse, and pitfalls of the drug challenge test in the diagnosis of the Brugada syndrome


Pacing or ablation for vasovagal syncope: one size does not fit all


Impact of early vs. delayed atrial fibrillation catheter ablation on atrial arrhythmia recurrences


Short-duration head-up tilt test potentiated with sublingual nitroglycerin in suspected vasovagal syncope: the fast Italian protocol


Safety and Effectiveness of Pulsed Field Ablation to Treat Atrial Fibrillation: One-Year Outcomes from the MANIFEST-PF Registry


Cognitive Behavioral Therapy Improves Quality of Life in Patients with Symptomatic Paroxysmal Atrial Fibrillation


Individualized Family Screening for Arrhythmogenic Right Ventricular Cardiomyopathy


Comparison of Left Bundle Branch Area Pacing and Biventricular Pacing in Candidates for Resynchronization Therapy


Evaluation of a new treadmill exercise protocol to unmask type 1 Brugada electrocardiographic pattern: can we improve diagnostic yield?


Age-stratified comparison of prognosis in cardiac resynchronization therapy with or without prophylactic defibrillator for nonischemic cardiomyopathy—a nationwide cohort study


Pulsed Field versus Cryoballoon Pulmonary Vein Isolation for Atrial Fibrillation: Efficacy, Safety, and Long-Term Follow-Up in a 400-Patient Cohort


Action Potential Morphology Accurately Predicts Proarrhythmic Risk for Drugs with Potential to Prolong Cardiac Repolarization


Mitral Annular Substrate and Ventricular Arrhythmias in Arrhythmogenic Mitral Valve Prolapse with Mitral Annular Disjunction


Post-Shock Asystole in Patients Dying Out of Hospital While Wearing a Cardioverter Defibrillator


Pulmonary Artery Denervation Inhibits Left Stellate Ganglion Stimulation-Induced Ventricular Arrhythmias Originating From the RVOT


Comparison of Pacing Performance and Clinical Outcomes between Left Bundle Branch and His Bundle Pacing


Ventricular Parasystole in Cardiomyopathy Patients: A Link between His-Purkinje System Damage and Ventricular Fibrillation




Comparative effectiveness of SGLT2 inhibitors, GLP-1 receptor agonists, DPP-4 inhibitors, and sulfonylureas on risk of major adverse cardiovascular events: emulation of a randomized target trial using electronic health records


Moderate-Intensity Statin with Ezetimibe Combination Therapy vs High-Intensity Statin Monotherapy in Patients at Very High Risk of Atherosclerotic Cardiovascular Disease: RACING Randomized Clinical Trial.


Great debate: lipid-lowering therapies should be guided by vascular imaging rather than by circulating biomarkers


Great Debate: Computed tomography coronary angiography should be the initial diagnostic test in suspected angina


Vegetarian or vegan diets and blood lipids: a meta-analysis of randomized trials


Red meat consumption, cardiovascular diseases, and diabetes: a systematic review and meta-analysis


Treatment Strategies for Cardiomyopathy in Children: A Scientific Statement from the American Heart Association


Long-Term Outcomes of Women with Peripartum Cardiomyopathy Having Subsequent Pregnancies


P2Y12 Inhibitor or Aspirin Monotherapy for Secondary Prevention of Coronary Events


Consumer Wearable Health and Fitness Technology in Cardiovascular Medicine: JACC State-of-the-Art Review


Role of Human Epicardial Adipose Tissue–Derived miR-92a-3p in Myocardial Redox State


Cardiac Myosin Inhibitors for Managing Obstructive Hypertrophic Cardiomyopathy:

JACC: Heart Failure State-of-the-Art Review


Management of Heart Failure–Related Cardiogenic Shock: Practical Guidance for Clinicians


24.07.2023: My June Electrophysiology and Cardiology Selection:


Association between Syncope Trigger Type and Risk of Subsequent Life-Threatening Events in Patients with Long QT Syndrome


Direct Oral Anticoagulants versus Warfarin across the Spectrum of Kidney Function: Patient-Level Network Meta-Analyses from COMBINE AF


CIB2 Is a Novel Endogenous Repressor of Atrial Remodeling


Effects of Atrial Fibrillation Screening According to N-Terminal Pro-B-Type Natriuretic Peptide: A Secondary Analysis of the Randomized LOOP Study


Multidisciplinary Critical Care Management of Electrical Storm: JACC State-of-the-Art Review


Ventricular Arrhythmias Associated with Over-the-Counter and Recreational Opioids


Pathogenesis, Evaluation, and Management of Pulmonary Vein Stenosis: JACC Review Topic of the Week


Silent cerebral lesions following catheter ablation for atrial fibrillation: a state-of-the-art review


Stepwise application of ECG and electrogram-based criteria to ensure electrical resynchronization with left bundle branch pacing


The R″ wave in V1 and the negative terminal QRS vector in aVF combine to a novel 12-lead ECG algorithm to identify slow conducting anatomical isthmus 3 in patients with tetralogy of Fallot


Cost-effectiveness of an antibacterial envelope for infection prevention in patients undergoing cardiac resynchronization therapy reoperations in Denmark


Identifying the prognostic significance of early arrhythmia recurrence during the blanking period and the optimal blanking period duration: insights from the DECAAF II study


Head-to-Head Comparison of T1 Mapping and Electroanatomical Voltage Mapping in Patients with Ventricular Arrhythmias


Evolution of Deceleration Zones during Ventricular Tachycardia Ablation and Relation with Cardiac Magnetic Resonance


Causes of Early Mortality after Ventricular Tachycardia Ablation in Patients with Reduced Ejection Fraction


Matching Ablation Endpoints to Long-Term Outcome: The Prospective Multicenter Italian Ventricular Tachycardia Ablation Registry


Effects of Atrioventricular Optimization on Left Ventricular Reverse Remodeling With Cardiac Resynchronization Therapy: Results of the SMART-CRT Trial


Stellate ganglion instrumentation for pharmacological blockade, nerve recording, and stimulation in patients with ventricular arrhythmias: Preliminary experience


Sinus rhythm electrocardiographic abnormalities, sites of origin, and ablation outcomes of ventricular premature depolarizations initiating ventricular fibrillation


Vagal response is involved in the occurrence of ventricular fibrillation in patients with early repolarization syndrome


Device–device interaction between cardiac implantable electronic devices and continuous-flow left ventricular assist devices


Catheter and surgical ablation for ventricular tachycardia in patients with left ventricular assist devices



Zilebesiran, an RNA Interference Therapeutic Agent for Hypertension


Phase 1 Trial of Antibody NI006 for Depletion of Cardiac Transthyretin Amyloid


Heart-brain connections: Phenotypic and genetic insights from magnetic resonance images


Remote haemodynamic monitoring of pulmonary artery pressures in patients with chronic heart failure (MONITOR-HF): a randomised clinical trial


Digitalis in heart failure: declining use and ongoing outcome trials


Hypertension management in patients with cardiovascular comorbidities


Great debate: in patients with decompensated heart failure, acetazolamide in addition to loop diuretics is the first choice


Spatial Transcriptional Mapping Reveals Site-Specific Pathways Underlying Human Atherosclerotic Plaque Rupture


Remote Monitoring for Heart Failure Management at Home: JACC Scientific Statement


Association of Beta-Blocker Therapy with Cardiovascular Outcomes in Patients with Stable Ischemic Heart Disease


How to Manage Heart Failure with Preserved Ejection Fraction: Practical Guidance for Clinicians


22.06.2023: My May Electrophysiology Selection:

The R-wave amplitude in V1 on baseline electrocardiogram correlates with the occurrence of high-degree atrioventricular block following left bundle branch block after trans-catheter aortic valve replacement


Ventricular rate in atrial fibrillation and the risk of heart failure and death


Treatment of pathophysiologic propagation outside of the pulmonary veins in retreatment of atrial fibrillation patients: RECOVER AF study


Efficacy and safety in patients treated with a novel radiofrequency balloon: a two centers experience from the AURORA collaboration


Catheter ablation of atrial fibrillation and atrial tachycardia in patients with pulmonary hypertension: a randomized study


Randomized Trial of Stand-Alone Use of the Antimicrobial Envelope in High-Risk Cardiac Device Patients


Outcomes of Early Rhythm Control Therapy in Patients with Atrial Fibrillation and a High Comorbidity Burden in Large Real-World Cohorts


Novel Approaches for the Diagnosis of Concealed Nodo-Ventricular and His-Ventricular Pathways


Pulmonary Vein Isolation with and Without Posterior Wall Isolation in Paroxysmal Atrial Fibrillation: IMPPROVE-PAF Trial


Left Atrial Appendage Occlusion in the Elderly: Insights from PROTECT-AF, PREVAIL, and Continuous Access Registries


Multipolar Ablation Using Mapping Electrodes: A Novel Approach to Intramural Arrhythmia Substrates


Failure of Intrinsic Antitachycardia Pacing to Terminate Ventricular Tachycardia and Potential Proarrhythmic Effects


Anterior mitral line in patients with persistent atrial fibrillation and anterior scar: A multicenter matched comparison—The MiLine study


Electrocardiographic and electrophysiological characteristics of ventricular arrhythmias from the right bundle branch of the moderator band


Right ventricular cardiac resynchronization therapy in patients with right ventricular conduction delay and heart failure


Regression of cardiac hypertrophy in health and disease: mechanisms and therapeutic potential


Reversal and removal of oral antithrombotic drugs in patients with active or perceived imminent bleeding


Reversal agents for current and forthcoming direct oral anticoagulants


Outcomes of patients with atrial fibrillation and ischemic stroke while on oral anticoagulation


2023 HRS/EHRA/APHRS/LAHRS Expert Consensus Statement on Practical Management of the Remote Device Clinic


Should lethal arrhythmias in hypertrophic cardiomyopathy be predicted using non-electrophysiological methods?


Electrocardiographic markers of subclinical atrial fibrillation detected by implantable loop recorder: insights from the LOOP Study


Evidence for concealed fasciculo-ventricular connections as revealed by His bundle pacing


Time of onset of atrial fibrillation and atrial fibrillation progression data from the RACE V study


Timing of cardiac resynchronization therapy implantation


Dynamic changes in nocturnal heart rate predict short-term cardiovascular events in patients using the wearable cardioverter-defibrillator: from the WEARIT-France cohort study


29.04.2023: My April's EP, AI and Cardiology Selection:



Impact of Early Versus Delayed Atrial Fibrillation Catheter Ablation on Atrial Arrhythmia Recurrences


A worldwide survey on incidence, management and prognosis of oesophageal fistula formation following atrial fibrillation catheter ablation: The POTTER-AF study.


EHRA clinical consensus statement on conduction system pacing implantation.


EHRA expert consensus document on the management of arrhythmias in frailty syndrome


Non-coding RNA and arrhythmias: expression, function, and molecular mechanism.


An artificial intelligence–based model for prediction of atrial fibrillation from single-lead sinus rhythm electrocardiograms facilitating screening.


Ambulatory pulmonary vein isolation workflow using the Perclose ProglideTM suture-mediated vascular closure device: the PRO-PVI study.


Mapping-guided atrial lead placement determines optimal conduction across Bachmann’s bundle: a rationale for patient-tailored pacing therapy.


Non-invasive three-dimensional electrical activation mapping to predict cardiac resynchronization therapy response: site of latest left ventricular activation relative to pacing site.


Single beta-blocker or combined amiodarone therapy in implantable cardioverter-defibrillator and cardiac resynchronization therapy—defibrillator patients: Insights from the German DEVICE registry.


New insights into atrioventricular nodal anatomy, physiology, and immunochemistry: A comprehensive review and a proposed model of the slow-fast atrioventricular nodal reentrant tachycardia circuit in agreement with direct potential recordings in the Koch’s triangle area.


New insights into the mechanisms of fast and slow conduction in the atrioventricular node


Bronchial Safety After Pulsed Field Ablation for Paroxysmal Atrial Fibrillation.


An Exercise and Physical Activity Program in Patients with Atrial Fibrillation: The ACTIVE-AF Randomized Controlled Trial.


Pulsed Field Ablation to Treat Atrial Fibrillation: Autonomic Nervous System Effects.


Marked QTc Reduction Immediately Following Direct Current Cardioversion of Atrial Fibrillation: Clinical Implications and Mechanisms.


Risks of Heart Failure, Stroke, and Bleeding in Atrial Fibrillation According to Heart Failure Phenotypes.


Kinase Inhibitors and Atrial Fibrillation: Mechanisms of Action and Clinical Implications.




Dietary Sodium Restriction in Patients with Heart Failure.


Phase 3 Trial of Sotatercept for Treatment of Pulmonary Arterial Hypertension.


Genome editing prevents hypertrophic cardiomyopathy in mice.


Temporary mechanical circulatory support devices: practical considerations for all stakeholders.


Effect of Dapagliflozin on Total Heart Failure Events in Patients with Heart Failure With Mildly Reduced or Preserved Ejection Fraction.


Myocardial Metabolomics of Human Heart Failure with Preserved Ejection Fraction


Transiently achieved very low low-density lipoprotein cholesterol levels by statin and alirocumab after acute coronary syndrome are associated with cardiovascular risk reduction: the ODYSSEY OUTCOMES trial.


Association Between Achieved Low-Density Lipoprotein Cholesterol Levels and Long-Term Cardiovascular and Safety Outcomes: An Analysis of FOURIER-OLE.


Overcoming professional barriers encountered by women in interventional cardiology: an EAPCI statement.


Variation in Renal Function Following Transition to Sacubitril/Valsartan in Patients with Heart Failure.


Heart Failure Following Anti-Inflammatory Medications in Patients with Type 2 Diabetes Mellitus.


Artificial Intelligence:


Readiness for implementation of novel digital health interventions for postoperative monitoring: a systematic review and clinical innovation network analysis.


Does deidentification of data from wearable devices give us a false sense of security? A systematic review.


Validation of a novel numerical model to predict regionalized blood flow in the coronary arteries.


Premature atrial and ventricular contractions detected on wearable-format electrocardiograms and prediction of cardiovascular events.


Machine learning in sudden cardiac death risk prediction: a systematic review.


06.03.2023: My current EP and Cardiology Selection:

Artificial Intelligence:

How to regulate evolving AI health algorithms


Characterizing cyber harms from digital health


Implementing clinical trial data sharing requires training a new generation of biomedical researchers


A call for deep-learning healthcare



Type 2 DM and higher rate of complete atrioventricular block: a Danish Nationwide Registry


Impact of Low Body Mass Index on Cardiac Tamponade during Catheter Ablation for Atrial Fibrillation


Systemic Delivery of Extracellular Vesicles Attenuates Atrial Fibrillation in Heart Failure with Preserved Ejection Fraction


Initial Findings from the National Cardiovascular Data Registry of Atrial Fibrillation Ablation Procedures


Temporal and Spatial Changes of Proarrhythmic Substrate in Premature Ventricular Contraction–Induced Cardiomyopathy


Left and Right PVC-Induced Ventricular Dysfunction


Effect of Direct Slow Pathway Capture Mapping–Guided Ablation on Typical Atrioventricular Nodal Re-Entrant Tachycardia


The Value of Programmed Ventricular Extrastimuli From the Right Ventricular Basal Septum During Supraventricular Tachycardia


Substrate Mapping Alters Ventricular Tachycardia Inducibility


Reduction in Junctophilin 2 Expression in Cardiac Nodal Tissue Results in Intracellular Calcium-Driven Increase in Nodal Cell Automaticity


Recurrences of Atrial Fibrillation Despite Durable Pulmonary Vein Isolation: The PARTY-PVI Study


Novel Ablation Strategy Targeting the Slow Pathway Visualized by Ultrahigh-Resolution Mapping in Typical Slow-Fast Atrioventricular Nodal Reentrant Tachycardia



Five-Year Follow-up after Transcatheter Repair of Secondary Mitral Regurgitation


Intravascular Imaging–Guided or Angiography-Guided Complex PCI


Transcatheter Repair for Patients with Tricuspid Regurgitation


Bempedoic Acid and Cardiovascular Outcomes in Statin-Intolerant Patients


Effectiveness, reach, uptake, and feasibility of digital health interventions for adults with type 2 diabetes: a systematic review and meta-analysis of randomised controlled trials


Effectiveness, reach, uptake, and feasibility of digital health interventions for adults with hypertension: a systematic review and meta-analysis of randomised controlled trials


Performance of the European Society of Cardiology 0/1-Hour Algorithm with High-Sensitivity Cardiac Troponin T Among Patients With Known Coronary Artery Disease


Artificial intelligence to enhance clinical value across the spectrum of cardiovascular healthcare


Comparison Of 3-6 Month Versus 12 Month Dual Antiplatelet Therapy After Coronary Intervention Using the Contemporary Drug-eluting Stents With Ultrathin Struts: The HOST-IDEA Randomized Clinical Trial


Prevalence and Clinical Implications of Tricuspid Valve Prolapse Based on Magnetic Resonance Diagnostic Criteria


Pericoronary Adipose Tissue as a Marker of Cardiovascular Risk: JACC Review Topic of the Week


19.02.2023: My current EP and Cardiology Selection:



Retrospective Window of Interest Annotation Provides New Insights into Functional Channels in Ventricular Tachycardia Substrate


Importance of Right Ventricular Mapping and Ablation for Ventricular Tachycardia in Postinfarction Patients


Cardioneuroablation for Reflex Syncope: Efficacy and Effects on Autonomic Cardiac Regulation—A Prospective Randomized Trial


Isoproterenol-Assisted Differentiation between Sludge and Organized Thrombus to Guide Left Atrial Appendage Occlusion


Cardiac Repolarization in Health and Disease: State-Of-The-Art Review


Prevalence and Prognostic Significance of Bradyarrhythmias in Patients Screened for Atrial Fibrillation vs Usual Care: Post Hoc Analysis of the LOOP Randomized Clinical Trial


Association of Left Atrial Strain with Ischemic Stroke Risk in Older Adults


Genetic variants associated with syncope implicate neural and autonomic processes


Value of screening for the risk of sudden cardiac death in young competitive athletes


Comparative Effectiveness and Safety of Direct Oral Anticoagulants and Warfarin in Patients with Atrial Fibrillation and Chronic Liver Disease: A Nationwide Cohort Study


Combined Minimally Invasive Surgical and Percutaneous Catheter Ablation of Atrial Fibrillation: JACC Review Topic of the Week


Association between Number of Volunteer Responders and Interventions before Ambulance Arrival for Cardiac Arrest



Phase 2 Trial of Baxdrostat for Treatment-Resistant Hypertension


The next generation of evidence-based medicine


Carotid endarterectomy or stenting or best medical treatment alone for moderate-to-severe asymptomatic carotid artery stenosis: 5-year results of a multicentre, randomised controlled trial


Machine learning for classification of hypertension subtypes using multi-omics: A multi-centre, retrospective, data-driven study


Renal denervation in the management of hypertension in adults.


Immunodeficiency is prevalent in congenital heart disease and associated with increased risk of emergency admissions and death


Rule-out of non-ST-segment elevation acute coronary syndrome by a single, pre-hospital troponin measurement: a randomized trial


Anesthetic Care of the Pregnant Patient with Cardiovascular Disease: A Scientific Statement from the American Heart Association


P2Y12 Inhibitor Monotherapy or Dual Antiplatelet Therapy after Complex Percutaneous Coronary Interventions


Prevalence and Professional Impact of Mental Health Conditions among Cardiologists


Intravascular Imaging during Percutaneous Coronary Intervention: JACC State-of-the-Art Review


Left Ventricular Filling Pressure in Chronic Thromboembolic Pulmonary Hypertension


Bleeding Events after Transcatheter Aortic Valve Replacement: JACC State-of-the-Art Review


Approaches to Genetic Screening in Cardiomyopathies: Practical Guidance for Clinicians


Longer-Term Effects of Remote Patient Management Following Hospital Discharge after Acute Systolic Heart Failure: The Randomized E-INH Trial


Cardiopulmonary Exercise Testing With Simultaneous Echocardiography: Blueprints of a Dyspnea Clinic for Suspected HFpEF


30.01.2023: My current EP and Cardiology Selection:


Abnormal Conduction Zone Detected by Isochronal Late Activation Mapping Accurately Identifies the Potential Atrial Substrate and Predicts the Atrial Fibrillation Ablation Outcome after Pulmonary Vein Isolation


Investigator-reported ventricular arrhythmias and mortality in heart failure with mildly reduced or preserved ejection fraction


Cardiac Resynchronization Therapy Improves Outcomes in Patients with Intraventricular Conduction Delay but Not Right Bundle Branch Block: A Patient-Level Meta-Analysis of Randomized Controlled Trials


Pleomorphic Ventricular Tachycardia in Dilated Cardiomyopathy Predicts Ventricular Tachycardia Recurrence after Ablation Independent from Cardiac Function: Comparison with Patients with Ischemic Heart Disease


Chronic Kidney Disease Induces Proarrhythmic Remodeling


Electrophysiology, Pathology, and Imaging of PFA of Scarred and Healthy Ventricles in Swine


Atrial Endocardial Unipolar Voltage Mapping for Detection of Viable Intramural Myocardium


Premature Atrial Contraction Location and Atrial Fibrillation Inducibility



Cystatin C–Based Equation to Estimate GFR without the Inclusion of Race and Sex


Early Extracorporeal CPR for Refractory Out-of-Hospital Cardiac Arrest


Performance of cardiovascular disease risk prediction equations in more than 14 000 survivors of cancer in New Zealand primary care: a validation study


Association of Rurality with Risk of Heart Failure


The year in cardiovascular medicine 2022: the top 10 papers in dyslipidaemias


The year in cardiovascular medicine 2022: the top 10 papers in interventional cardiology


Factor XI inhibitors: cardiovascular perspectives


Acute, periprocedural and long-term antithrombotic therapy in older adults: 2022 Update by the ESC Working Group on Thrombosis


Interleukin-33 Mediates Cardiomyopathy after Acute Kidney Injury by Signaling to Cardiomyocytes


Thromboprophylaxis in Patients With Fontan Circulation


Infective Endocarditis after Transcatheter Aortic Valve Replacement: JACC State-of-the-Art Review


Worsening Heart Failure: Nomenclature, Epidemiology, and Future Directions


14.01.2023: My current EP and Cardiology Selection:


Regional Antibiotic Delivery for Implanted Cardiovascular Electronic Device Infections


Impact of Left Ventricular Papillary Muscle Ventricular Arrhythmia Ablation on Mitral Valve Function


Effect of Epicardial Pulsed Field Ablation Directly on Coronary Arteries


QT Prolongation and In-Hospital Ventricular Arrhythmic Complications in Patients with Apical Ballooning Takotsubo Syndrome


Safety of Pill-in-the-Pocket Class 1C Antiarrhythmic Drugs for Atrial Fibrillation


Serial 7-Day ECG Patch Screening for AF in High-Risk Older Women by the CHARGE-AF Score


Ventricular Arrhythmias and Implantable Cardioverter-Defibrillator Therapy in Women: A Propensity Score-Matched Analysis


Advances of Implantation Techniques for Conduction System Pacing



Circulating Spike Protein Detected in Post–COVID-19 mRNA Vaccine Myocarditis


Trial of an Intervention to Improve Acute Heart Failure Outcomes


Chlorthalidone vs. Hydrochlorothiazide for Hypertension–Cardiovascular Events


Cardiac troponin release following coronary artery bypass grafting: mechanisms and clinical implications


Coronary microvascular dysfunction is associated with impaired cognitive function: the Cerebral-Coronary Connection study (C3 study)


Exercise Volume versus Intensity and the Progression of Coronary Atherosclerosis in Middle-Aged and Older Athletes: Findings from the MARC-2 Study


Targeting Epsins to Inhibit Fibroblast Growth Factor Signaling While Potentiating Transforming Growth Factor-β Signaling Constrains Endothelial-to-Mesenchymal Transition in Atherosclerosis


Takayasu Arteritis: JACC Focus Seminar 3/4


Nutritional Heart Disease and Cardiomyopathies: JACC Focus Seminar 4/4


Prediction of Left Ventricular Ejection Fraction Change Following Treatment with Sacubitril/Valsartan


Prediction of LV Reverse Remodeling and Outcomes by Circulating Collagen-Derived Peptides


03.01.2023: My New Year EP and Cardiology Selection:


Chlorthalidone vs. Hydrochlorothiazide for Hypertension–Cardiovascular Events


Machine learning-based marker for CAD: derivation and validation in two longitudinal cohorts


Association of the triglyceride glucose index as a measure of insulin resistance with mortality and cardiovascular disease in populations from five continents (PURE study): a prospective cohort study


Predictive Utility of a Coronary Artery Disease Polygenic Risk Score in Primary Prevention


Valvular heart disease: shifting the focus to the myocardium


Impact of empagliflozin on decongestion in acute heart failure: the EMPULSE trial


Peptide Vaccine against ADAMTS-7 Ameliorates Atherosclerosis and Postinjury Neointima Hyperplasia


Survival after Invasive or Conservative Management of Stable Coronary Disease


Comparative Effects of Low-Dose Rosuvastatin, Placebo, and Dietary Supplements on Lipids and Inflammatory Biomarkers


Direct Oral Anticoagulants vs Vitamin K Antagonists in Patients with Antiphospholipid Syndromes: Meta-Analysis of Randomized Trials


Infections and Cardiovascular Disease: JACC Focus Seminar 1/4


Rheumatic Heart Disease: JACC Focus Seminar 2/4



Early rhythm-control therapy for atrial fibrillation in patients with a history of stroke: a subgroup analysis of the EAST-AFNET 4 trial


Fit for the future: empowering clinical trials with digital technology


Clinical benefits of concomitant surgical ablation for AF in patients undergoing mitral valve surgery


Outcomes in patients with electrocardiographic left ventricular dyssynchrony following transcatheter aortic valve replacement


Differences in mode of death between men and women receiving implantable cardioverter-defibrillators or cardiac resynchronization therapy in the MADIT trials


Left bundle area pacing: Guiding implant depth by ring measurements


Neuromodulation therapy for atrial fibrillation


Characterization of ventricular arrhythmias and sudden cardiac death in subjects with mitral valve prolapse and mitral annular disjunction


Three-dimensional functional anatomy of the human sinoatrial node for epicardial and endocardial mapping and ablation


Outcomes of a PAINESD score–guided multidisciplinary management approach for patients with ventricular tachycardia storm and advanced heart failure


16.11.2022: My Current EP and Cardiology Selection:


Bleeding and ischemic events after first bleed in anticoagulated atrial fibrillation patients: risk and timing


Cost-effectiveness of population screening for atrial fibrillation: the STROKESTOP study


Bone morphogenetic protein 10: a novel risk marker of ischemic stroke in patients with atrial fibrillation


Ventricular fibrillation in acute myocardial infarction: 20-year trends in the FAST-MI study


Rhythm monitoring, success definition, recurrence, and anticoagulation after atrial fibrillation ablation: results from an EHRA survey


Non-invasive localization of post-infarct ventricular tachycardia exit sites to guide ablation planning: a computational deep learning platform utilizing the 12-lead electrocardiogram and intracardiac electrograms from implanted devices


Upgrading right ventricular pacemakers to biventricular pacing or conduction system pacing: a systematic review and meta-analysis


Disease progression rate is a strong predictor of ventricular arrhythmias in patients with cardiac laminopathies: a primary prevention cohort study


Repeatability of ventricular arrhythmia characteristics on the exercise-stress test in RYR2-mediated catecholaminergic polymorphic ventricular tachycardia


A head-to-head comparison of laser vs. powered mechanical sheaths as first choice and second line extraction tools


Left bundle branch area pacing in congenital heart disease



Effects of Renal Denervation vs Sham in Resistant Hypertension after Medication Escalation: RADIANCE-HTN TRIO Randomized Clinical Trial.


Coronary microvascular dysfunction is associated with impaired cognitive function: the cerebral-coronary connection study (C3 study)


Patient selection for long-term secondary prevention with ticagrelor: insights from PEGASUS-TIMI 54


Surgical or Percutaneous Coronary Revascularization for Heart Failure: An In Silico Model using Routinely Collected Health Data to Emulate a Clinical Trial.


Single-cell technologies to decipher cardiovascular diseases


An Overview of Telehealth in the Management of Cardiovascular Disease: A Scientific Statement from the American Heart Association


Artificial Intelligence for Contrast-Free MRI: Scar Assessment in Myocardial Infarction Using Deep Learning–Based Virtual Native Enhancement


Coronary Calcium Scoring Improves Risk Prediction in Patients with Suspected Obstructive Coronary Artery Disease


Prognostic Prediction of Genotype vs Phenotype in Genetic Cardiomyopathies


Outcomes of Pregnancy in Women with Bioprosthetic Heart Valves with or without Valve Dysfunction


Randomized Trials of Percutaneous Microaxial Flow Pump Devices: JACC State-of-the-Art Review


08.11.2022: My Current EP and Cardiology Selection from AHA2022


Impact of Low Body Mass Index on Cardiac Tamponade During Catheter Ablation for Atrial Fibrillation


Subcutaneous and Transvenous Defibrillators in Arrhythmogenic Right Ventricular Cardiomyopathy: A Comparison of Clinical and Quality-of-Life Outcomes


Causes of Early Mortality After Ventricular Tachycardia Ablation in Patients with Reduced Ejection Fraction


Direct Oral Anticoagulants vs Vitamin-K Antagonists in Thrombotic Antiphospholipid Syndrome: Meta-analysis of Randomized Controlled Trials


Relationship Between Periodontitis and Atrial Fibrosis in Atrial Fibrillation: Histological Evaluation of Left Atrial Appendages


Progression of Atrial Fibrillation after Cryoablation or Drug Therapy


Defibrillation Strategies for Refractory Ventricular Fibrillation



Surgery or Endovascular Therapy for Chronic Limb-Threatening Ischemia


Phase 2 Trial of Baxdrostat for Treatment-Resistant Hypertension


Small Interfering RNA to Reduce Lipoprotein(a) in Cardiovascular Disease


Triglyceride Lowering with Pemafibrate to Reduce Cardiovascular Risk


Trial of an Intervention to Improve Acute Heart Failure Outcomes: the COACH Trial.


Dual endothelin antagonist aprocitentan for resistant hypertension (PRECISION): a multicentre, blinded, randomised, parallel-group, phase 3 trial


Safety, tolerability and efficacy of up-titration of guideline-directed medical therapies for acute heart failure (STRONG-HF): a multinational, open-label, randomised, trial


Bivalirudin plus a high-dose infusion versus heparin monotherapy in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: a randomised trial


Intravenous ferric derisomaltose in patients with heart failure and iron deficiency in the UK (IRONMAN): an investigator-initiated, prospective, randomised, open-label, blinded-endpoint trial


Incidental Coronary Artery Calcium: Opportunistic Screening of Prior Non-gated Chest CTs to Improve Statin Rates (NOTIFY-1 Project)


Aspirin vs. Clopidogrel for Chronic Maintenance Monotherapy after Percutaneous Coronary Intervention: the HOST-EXAM Extended Study


Exercise for the Prevention of Anthracycline-induced Functional Disability and Cardiac Dysfunction: The BReast Cancer Randomized EXercise InTervention (BREXIT) Study


Comparative Effects of Low-Dose Rosuvastatin, Placebo and Dietary Supplements on Lipids and Inflammatory Biomarkers


Artificial Intelligence:

Concordance Between Patient-Reported Health Data and Electronic Health Data


Individualising intensive systolic blood pressure reduction in hypertension using computational trial phenomaps and machine learning: a post-hoc analysis of randomised clinical trials


24.10.2022: My Current EP and Cardiology Selection


Percutaneous Revascularization for Ischemic Left Ventricular Dysfunction


Five-Year Outcomes of the Danish Cardiovascular Screening (DANCAVAS) Trial


Acetazolamide in Acute Decompensated Heart Failure with Volume Overload


Cerebral Embolic Protection during Transcatheter Aortic-Valve Replacement


Cardiovascular outcomes in adults with hypertension with evening versus morning dosing of usual antihypertensives in the UK (TIME study): a prospective, randomized, open-label, blinded-endpoint clinical trial


Allopurinol versus usual care in UK patients with ischemic heart disease (ALL-HEART): a multicenter, prospective, randomized, open-label, blinded-endpoint trial


Longer-Term All-Cause and Cardiovascular Mortality with Intensive Blood Pressure Control: A Secondary Analysis of a Randomized Clinical Trial


Association between hypotension during 24 h ambulatory blood pressure monitoring and reflex syncope: the SynABPM 1 study


Aldosterone in chronic kidney disease and renal outcomes


Phenotyping the hypertensive heart


Intensive Blood Pressure Lowering in Patients with Malignant Left Ventricular Hypertrophy


Dose-Response to Sacubitril/Valsartan in Patients with Heart Failure and Reduced Ejection Fraction


Acute Myocarditis Associated With Desmosomal Gene Variants


A Multicenter, Phase 2, Randomized, Placebo-Controlled, Double-Blind, Parallel-Group, Dose-Finding Trial of the Oral Factor XIa Inhibitor Asundexian to Prevent Adverse Cardiovascular Outcomes after Acute Myocardial Infarction


Impact of Periprocedural Pulmonary Hypertension on Outcomes after Transcatheter Aortic Valve Replacement


Noninvasive Physiologic Assessment of Cardiac Allograft Vasculopathy Is Prognostic for Post-Transplant Events


Diaphragmatic Function in Cardiovascular Disease: JACC Review Topic of the Week



Programmed Ventricular Stimulation as an Additional Primary Prevention Risk Stratification Tool in Arrhythmogenic Right Ventricular Cardiomyopathy: A Multinational Study


Highly malignant disease in childhood-onset arrhythmogenic right ventricular cardiomyopathy


Cannabis, cocaine, methamphetamine, and opiates increase the risk of incident atrial fibrillation


Factor XI inhibitors: cardiovascular perspectives


Risk factors for cardiac implantable electronic device infections: a nationwide Danish study


Malignant Purkinje ectopy induced by sodium channel blockers


Characterization of the right ventricular substrate participating in postinfarction ventricular tachycardia


Predicting arrhythmia recurrence following catheter ablation for ventricular tachycardia using late gadolinium enhancement magnetic resonance imaging: Implications of varying scar ranges


Terminal end of retro-aortic root branch: An unrecognized origin for “proximal left anterior fascicle” premature ventricular complexes with narrow QRS duration


Magnetic resonance imaging and histopathology of catheter ablation lesions after ventricular tachycardia ablation in patients with nonischemic cardiomyopathy


Value of genetic testing in the diagnosis and risk stratification of arrhythmogenic right ventricular cardiomyopathy


12.10.2022: My Current EP Selection


Association between left atrial epicardial fat, left atrial volume, and the severity of atrial fibrillation


Pulsed Field Ablation of the Porcine Ventricle Using a Focal Lattice-Tip Catheter


Substrate Characterization and Outcomes of Catheter Ablation of Ventricular Arrhythmias in Patients with Mitral Annular Disjunction


Sinus Tachycardia: a Multidisciplinary Expert Focused Review


Composite Index Tagging for PVI in Paroxysmal AF: A Prospective, Multicenter Post-approval Study


Incidence and Predictors of Early Death in Patients Undergoing Percutaneous Left Atrial Appendage Closure


Bipolar Electroporation across the Interventricular Septum: Electrophysiological, Imaging, and Histopathological Characteristics


Cardiac Magnetic Resonance in the Evaluation of Patients with Frequent Premature Ventricular Complexes


Increasing Lesion Dimensions of Bipolar Ablation by Modulating the Surface Area of the Return Electrode


Ablation of Refractory Ventricular Tachycardia Using Intramyocardial Needle Delivered Heated Saline-Enhanced Radiofrequency Energy: A First-in-Man Feasibility Trial


Multielectrode Contact Measurement Can Improve Long-Term Outcome of Pulmonary Vein Isolation Using Circular Single-Pulse Electroporation Ablation


Advanced Techniques for Ethanol Ablation of Left Ventricular Summit Region Arrhythmias


Machine Learning–Enabled Multimodal Fusion of Intra-Atrial and Body Surface Signals in Prediction of Atrial Fibrillation Ablation Outcomes


07.10.2022: My Current EP and CardiologySelection


Aldehyde dehydrogenase 2 and arrhythmogenesis


Near-infrared sensitive nanoparticle-mediated photothermal ablation of ventricular myocardium


Revaluing ablation therapy: History, recent developments, and future Heart Rhythm Society strategy


Impact of atrial fibrillation ablation on activity minutes in patients with cardiac implantable electronic devices


Long-term outcomes of left atrial appendage isolation using cryoballoon in persistent atrial fibrillation


Anatomical considerations and clinical interpretation of the 12-lead ECG in the prone position: a prospective multicenter study


Effect of repeat catheter ablation vs. antiarrhythmic drug therapy among patients with recurrent atrial tachycardia/atrial fibrillation after atrial fibrillation catheter ablation: data from CHINA-AF registry


Same-day discharge for atrial fibrillation ablation: outcomes and impact of ablation modality



Angiotensin receptor blockers and β blockers in Marfan syndrome: an individual patient data meta-analysis of randomised trials


Self-expanding Transcatheter vs Surgical Aortic Valve Replacement in Intermediate-Risk Patients: 5-Year Outcomes of the SURTAVI Randomized Clinical Trial


Impact on Mortality and Major Bleeding of Radial Versus Femoral Artery Access for Coronary Angiography or Percutaneous Coronary Intervention: a Meta-analysis of Individual Patient Data from Seven Multicenter Randomized Clinical Trials


Carotid endarterectomy or stenting or best medical treatment alone for moderate-to-severe asymptomatic carotid artery stenosis: 5-year results of a multicenter, randomized controlled trial


Association of Thoracic Aortic Aneurysm Size with Long-term Patient Outcomes, The KP-TAA Study


Scleraxis and fibrosis in the pressure-overloaded heart.


Left main coronary disease: evolving management concepts


Immunosuppressive therapy in virus-negative inflammatory cardiomyopathy: 20-year follow-up of the TIMIC trial


Aspirin for Primary Prevention of Cardiovascular Events in Relation to Lipoprotein(a) Genotypes


Early Versus Delayed Non–Vitamin K Antagonist Oral Anticoagulant Therapy After Acute Ischemic Stroke in Atrial Fibrillation (TIMING): A Registry-Based Randomized Controlled Non-inferiority Study


Cardiac Phenotypes in Secondary Hypertension: JACC State-of-the-Art Review


2022 ACC Expert Consensus Decision Pathway on the Role of Nonstatin Therapies for LDL-Cholesterol Lowering in the Management of Atherosclerotic Cardiovascular Disease Risk.


01.09.2022: My Current Cardiology and EP Selection


Aldosterone in chronic kidney disease and renal outcomes


Sex-specific evaluation and redevelopment of the GRACE score in non-ST-segment elevation acute coronary syndromes in populations from the UK and Switzerland: a multinational analysis with external cohort validation


Efficacy of telemedicine for the management of cardiovascular disease: a systematic review and meta-analysis


Empagliflozin in acute Myocardial Infarction: the EMMY trial


Cardiovascular complications of immune checkpoint inhibitors for cancer


CODE-EHR best practice framework for the use of structured electronic healthcare records in clinical research


Management of Infective Endocarditis in People Who Inject Drugs: A Scientific Statement from the American Heart Association


Randomized, Placebo-Controlled Phase 2b Study to Evaluate the Safety and Efficacy of Recombinant Human Lecithin Cholesterol Acyltransferase in Acute ST-Segment–Elevation Myocardial Infarction: Results of REAL-TIMI 63B


Screening for Cardiac Amyloidosis 5 to 15 Years after Surgery for Bilateral Carpal Tunnel Syndrome


Validated Model for Prediction of Adverse Cardiac Outcome in Patients with Fabry Disease


Ischemic Heart Disease in Young Women: JACC Review Topic of the Week



Rivaroxaban in Rheumatic Heart Disease–Associated Atrial Fibrillation


Attaining sinus rhythm mediates improved outcome with early rhythm control therapy of atrial fibrillation: the EAST – AFNET 4 trial


Highly malignant disease in childhood-onset arrhythmogenic right ventricular cardiomyopathy


Association of atrial depolarization variability and cardiac autonomic regulation with sudden cardiac death in coronary artery disease


Effectiveness and safety of mexiletine in patients at risk for (recurrent) ventricular arrhythmias: a systematic review


Predictors of recurrence after catheter ablation and electrical cardioversion of atrial fibrillation: an umbrella review of meta-analyse


ESC quality indicators for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: Developed in collaboration with the EHRA


Effect of continuous positive airway pressure therapy on recurrence of atrial fibrillation after pulmonary vein isolation in patients with obstructive sleep apnea: A randomized controlled trial


Impact of atrial fibrillation ablation on activity minutes in patients with cardiac implantable electronic devices


Secretome of atrial epicardial adipose tissue facilitates reentrant arrhythmias by myocardial remodeling


Intramyocardial mapping of ventricular premature depolarizations via septal venous perforators: Differentiating the superior intraseptal region from left ventricular summit origins


Contemporary maternal and fetal outcomes in the treatment of LQTS during pregnancy: Is nadolol bad for the fetus?


24.08.2022: My Current Cardiology and EP Selection


Safety of non-vitamin K antagonist oral anticoagulants: concerns in patients with atrial fibrillation and glomerular hyperfiltration?


Does SGLT1 inhibition add to the benefits of SGLT2 inhibition in the prevention and treatment of heart failure?


Sodium-Glucose Co-Transporter-2 Inhibitors and Cardiac Outcomes among Patients Treated With Anthracyclines


Supernormal Left Ventricular Ejection Fraction, Stroke Volume, and Cardiovascular Risk: Findings from Population-Based Cohort Studies


State of the Science: The Relevance of Symptoms in Cardiovascular Disease and Research: A Scientific Statement From the American Heart Association


Comparative Risks of Initial Aortic Events Associated With Genetic Thoracic Aortic Disease


Polygenic Risk Score Predicts Sudden Death in Patients with Coronary Disease and Preserved Systolic Function


Biomarker Prediction of Complex Coronary Revascularization Procedures in the FOURIER Trial


Severe Mental Illness and Cardiovascular Disease: JACC State-of-the-Art Review



Ancestry, Lipoprotein (a), and Cardiovascular Risk Thresholds: JACC Review Topic of the Week



Left bundle branch area pacing outcomes: the multicenter European MELOS study


Premature Ventricular Contractions Are Presaged by a Mechanically Abnormal Sinus Beat


The Association of Clustered Ventricular Arrhythmia and Cycle Length with Scar Burden in Cardiomyopathy


Insights from Simultaneous Left and Right Atrial Septal Mapping in Patients with Persistent Atrial Fibrillation


Use of Wearable Technology and Deep Learning to Improve the Diagnosis of Brugada Syndrome


Guideline-Directed Medical Therapy and the Risk of Death in Primary Prevention Defibrillator Recipients


Atrial Fibrillation and Stress: A 2-Way Street? State-Of-The-Art Review


Electromechanical reciprocity and arrhythmogenesis in long-QT syndrome and beyond


Implantable defibrillators in primary prevention of genetic arrhythmias. A shocking choice?


Arrhythmic risk prediction in arrhythmogenic right ventricular cardiomyopathy: external validation of the arrhythmogenic right ventricular cardiomyopathy risk calculator


Importance of genotype for risk stratification in arrhythmogenic right ventricular cardiomyopathy using the 2019 ARVC risk calculator


Importance of genetic testing in unexplained cardiac arrest


A new prediction model for ventricular arrhythmias in arrhythmogenic right ventricular cardiomyopathy


15.08.2022: My Current Cardiology and EP Selection


Screening for Atrial Fibrillation in Asymptomatic Older Adults


Critical appraisal of artificial intelligence-based prediction models for cardiovascular disease


Non-steroidal mineralocorticoid receptor antagonists in cardiorenal disease


Mendelian Randomization Study of PCSK9 and HMG-CoA Reductase Inhibition and Cognitive Function


Prevalence and Prognostic Implications of Discordant Grading and Flow-Gradient Patterns in Moderate Aortic Stenosis


Management of Patients with Severe Mitral Annular Calcification: JACC State-of-the-Art Review


Mitral Valve Dysfunction in Patients with Annular Calcification: JACC Review Topic of the Week


Routine Pressure Wire Assessment versus Conventional Angiography in the Management of Patients with Coronary Artery Disease: The RIPCORD 2 Trial



Assessment of the Diagnostic Yield of Combined Cardiomyopathy and Arrhythmia Genetic Testing


Post-operative atrial fibrillation and risk of heart failure hospitalization


Short- and Long-Term Risk of Lead Dislodgement Events: Real-World Experience from Product Surveillance Registry


Multielectrode Contact Measurement Can Improve Long-Term Outcome of Pulmonary Vein Isolation Using Circular Single-Pulse Electroporation Ablation


Advanced Techniques for Ethanol Ablation of Left Ventricular Summit Region Arrhythmias


Limitations of Unipolar Signals in Guiding Successful Outflow Tract Premature Ventricular Contraction Ablation


Impact of CPAP on the Atrial Fibrillation Substrate in Obstructive Sleep Apnea: The SLEEP-AF Study


Circumferential Pulmonary Vein Isolation plus Low-Voltage Area Modification in Persistent Atrial Fibrillation: The STABLE-SR-II Trial


Autonomic Changes Are More Durable After Radiofrequency than Pulsed Electric Field Pulmonary Vein Ablation


Safety and Efficacy of a Novel Blunt-Tip Concealed-Needle Epicardial Access Device: First-in-Human Feasibility Study


Short-Coupled Idiopathic Ventricular Fibrillation: A Literature Review with Extended Follow-Up


02.08.2022: My Current Cardiology and EP Selection


Balloon pulmonary angioplasty versus riociguat in inoperable chronic thromboembolic pulmonary hypertension (MR BPA): an open-label, randomised controlled trial


Hypertension in stroke survivors and associations with national premature stroke mortality: data for 2·5 million participants from multinational screening campaigns


Association between Early Left Ventricular Ejection Fraction Improvement after Transcatheter Aortic Valve Replacement and 5-Year Clinical Outcomes


Which patients with aortic stenosis should be referred to surgery rather than transcatheter aortic valve implantation?


Outcomes of culture-negative vs. culture-positive infective endocarditis: the ESC-EORP EURO-ENDO registry


Timing of cardiac surgery during pregnancy: a patient-level meta-analysis


Sleep-Disordered Breathing and Cardiac Arrhythmias in Adults: Mechanistic Insights and Clinical Implications: A Scientific Statement From the American Heart Association


Donor Macrophages Modulate Rejection after Heart Transplantation


Catastrophic Disruptions in Clinical Trials


Sustained-Release Ivabradine Hemisulfate in Patients with Systolic Heart Failure


Cardiorespiratory Fitness and Mortality Risk across the Spectra of Age, Race, and Sex


Deep Learning Electrocardiographic Analysis for Detection of Left-Sided Valvular Heart Disease



Atrial branch coronary artery stenosis as a mechanism for atrial fibrillation


Ultrasound-guided extracardiac vagal stimulation: new approach for visualization of the vagus nerve during cardioneuroablation


Clinical outcomes of conduction system pacing compared to biventricular pacing in patients requiring cardiac resynchronization therapy


Rescue left bundle branch area pacing in coronary venous lead failure or nonresponse to biventricular pacing: Results from International LBBAP Collaborative Study Group


Current of injury is an indicator of lead depth and performance during left bundle branch pacing lead implantation


SCN5A overlap syndromes: An open-minded approach


R-on-T and the initiation of reentry revisited: Integrating old and new concepts


23.07.2022: My Current AI Selection (Cardiology/EP)

22.07.2022: My Current Cardiology and EP Selection


Long-term efficacy and safety of moderate-intensity statin with ezetimibe combination therapy versus high-intensity statin monotherapy in patients with atherosclerotic cardiovascular disease (RACING).


Association of Left Ventricular Remodeling Assessment by Cardiac Magnetic Resonance with Outcomes in Patients with Chronic Aortic Regurgitation


Atrial septal defect in adulthood: a new paradigm for congenital heart disease


Left ventricular remodelling post-myocardial infarction: pathophysiology, imaging, and novel therapies


A systematic review and meta-analysis of beta-blockers and renin–angiotensin system inhibitors for preventing left ventricular dysfunction due to anthracyclines or trastuzumab in patients with breast cancer


Polygenic Risk Scores for Cardiovascular Disease: A Scientific Statement from the American Heart Association


Effect of Patient-Reported Preprocedural Physical and Mental Health on 10-Year Mortality After Percutaneous or Surgical Coronary Revascularization


Coronary In-Stent Restenosis: JACC State-of-the-Art Review


New Cardiovascular Risk Assessment Techniques for Primary Prevention: JACC Review Topic of the Week



Presenting Pattern of Atrial Fibrillation and Outcomes of Early Rhythm Control Therapy


Midodrine for the prevention of vasovagal syncope: a systematic review and meta-analysis


Diagnosis and management of arrhythmias in pregnancy


Estimated incidence of previously undetected atrial fibrillation on a 14-day continuous electrocardiographic monitor and associated risk of stroke


Does isolation of the left atrial posterior wall using cryoballoon ablation improve clinical outcomes in patients with persistent atrial fibrillation? A prospective randomized controlled trial


Ventricular tachycardia characteristics and outcomes with catheter ablation vs. antiarrhythmic therapy: insights from the VANISH trial


Long-term clinical impact of permanent pacemaker implantation in patients undergoing transcatheter aortic valve implantation: a systematic review and meta-analysis


Left ventricular shape predicts arrhythmic risk in fibrotic dilated cardiomyopathy


Theophylline in patients with syncope without prodrome, normal heart, and normal electrocardiogram: a propensity-score matched study verified by implantable cardiac monitor


A new score for life-threatening ventricular arrhythmias and sudden cardiac death in adults with transposition of the great arteries and a systemic right ventricle


08.07.2022: My Current Cardiology and EP Selection


Machine Learning–Based Models Incorporating Social Determinants of Health vs Traditional Models for Predicting In-Hospital Mortality in Patients With Heart Failure


Enoxaparin for primary thromboprophylaxis in symptomatic outpatients with COVID-19 (OVID): a randomised, open-label, parallel-group, multicentre, phase 3 trial


Targeting miR-30d reverses pathological cardiac hypertrophy


Deformation of Transcatheter Aortic Valve Prostheses: Implications for Hypoattenuating Leaflet Thickening and Clinical Outcomes


Circulating MicroRNA-122-5p Is Associated With a Lack of Improvement in Left Ventricular Function after Transcatheter Aortic Valve Replacement and Regulates Viability of Cardiomyocytes through Extracellular Vesicles


Prognostic impact of permanent pacemaker implantation after transcatheter aortic valve replacement


Characteristics of Heart Failure with Preserved Ejection Fraction across the Range of Left Ventricular Ejection Fraction


Carotid Artery Stenting: JACC State-of-the-Art Review


Remote and wearable ECG devices with diagnostic abilities in adults: A state-of-the-science scoping review



Evidence to support magnetic resonance conditional labelling of all pacemaker and defibrillator leads in patients with cardiac implantable electronic devices


Exercise training in heart failure with reduced ejection fraction and permanent atrial fibrillation: A randomized clinical trial


How to use bipolar and unipolar electrograms for selecting successful ablation sites of ventricular premature contractions


Successful avoidance of superior vena cava injury during transvenous lead extraction using a tandem femoral-superior approach


Predictors of perforation during lead extraction: Results of the Canadian Lead ExtrAction Risk study


Atrioventricular junction ablation in patients with conduction system pacing leads: A comparison of His-bundle vs left bundle branch area pacing leads


How to perform extrathoracic venous access for cardiac implantable electronic device placement: Detailed description of techniques


28.06.2022: My Current Cardiology and EP Selection


Associations between non-anemic iron deficiency and outcomes following elective cardiac surgery (IDOCS): a prospective cohort study


Biomarker-based risk model to predict cardiovascular events in patients with acute coronary syndromes – Results from BIPass registry


Novel Smooth Muscle Ca2+-Signaling Nanodomains in Blood Pressure Regulation


Cerebral Microbleeds during Transcatheter Aortic Valve Replacement: A Prospective Magnetic Resonance Imaging Cohort


Empagliflozin Improves Outcomes in Patients with Heart Failure and Preserved Ejection Fraction Irrespective of Age


Rivaroxaban and aspirin vs. aspirin alone in Asian compared with non-Asian patients with chronic coronary artery disease or peripheral arterial disease: the COMPASS trial



Frequency, Penetrance, and Variable Expressivity of Dilated Cardiomyopathy–Associated Putative Pathogenic Gene Variants in UK Biobank Participants


Cost-Effectiveness of Catheter Ablation versus Antiarrhythmic Drug Therapy in Atrial Fibrillation: The CABANA Randomized Clinical Trial


Fluoroless versus Conventional Mapping and Ablation of Ventricular Arrhythmias Arising From the Left Ventricular Summit and Interventricular Septum


5S Study: Safe and Simple Single Shot Pulmonary Vein Isolation with Pulsed Field Ablation Using Sedation


Mapping Atrial Fibrillation after Surgical Therapy to Guide Endocardial Ablation


Transesophageal Echocardiography Following Left Atrial Appendage Electrical Isolation: Diagnostic Pitfalls and Clinical Implications


Implantable defibrillators in primary prevention of genetic arrhythmias. A shocking choice?


17.06.2022: My Current Cardiology and EP Selection



Definitions and Standardized Endpoints for Treatment of Coronary Bifurcations

JACC State-Of-The-Art Review


Safety of Provocative Testing With Intracoronary Acetylcholine and Implications for Standard Protocols


False Lumen Flow Assessment by Magnetic Resonance Imaging and Long-Term Outcomes in Uncomplicated Aortic Dissection


Indoleamine 2,3-Dioxygenase 1 Deletion–Mediated Kynurenine Insufficiency in Vascular Smooth Muscle Cells Exacerbates Arterial Calcification


Combination Medical Therapy Benefit in Heart Failure with LVEF >45%


Intensive Blood Pressure Lowering in Older People with Hypertension: A Time-to-Benefit Analysis


Finding the “Sweet Spot” for High-Density Lipoprotein


Factors Associated with Physician Tolerance of Uncertainty: an Observational Study


Association of Thromboxane Generation with Survival in Aspirin Users and Nonusers




Inappropriate Sinus Tachycardia: Etiology, Pathophysiology, and Management.

JACC Review Topic of the Week


Association of Neighborhood-Level Material Deprivation with Atrial Fibrillation Care in a Single-Payer Health Care System: A Population-Based Cohort Study


Temporal Changes in Pulmonary Vein Reconnection during Repeat Catheter Ablation for Early Recurrence of Atrial Fibrillation


Continuous Pericardial Irrigation-Suction Technique to Manage Hemorrhagic Pericardial Effusion Associated With loculated Intrapericardial Thrombus


Simplified Integrated Clinical and Electrocardiographic Algorithm for Differentiation of Wide QRS-Complex Tachycardia: The Basel Algorithm


Short-Coupled Idiopathic Ventricular Fibrillation: A Literature Review with Extended Follow-Up


Pulsed Field Ablation of Left Ventricular Myocardium in a Swine Infarct Model


10.06.2022: My Current EP Selection

09.06.2022: My Current Cardiology Selection

06.06.2022: My Current EP Selection

Cardiac resynchronization therapy via left bundle branch pacing vs. optimized biventricular pacing with adaptive algorithm in heart failure with left bundle branch block: a prospective, multicenter, observational study


Machine learning–derived major adverse event prediction of patients undergoing transvenous lead extraction: Using the ESC EHRA EORP European lead extraction ConTRolled ELECTRa registry


Microbiological diagnosis in cardiac implantable electronic device infections detected by sonication and next-generation sequencing


Impact of baseline left ventricular volume on left ventricular reverse remodeling after cardiac resynchronization therapy


Electrical Posterior Box Isolation in Repeat Ablation for Atrial Fibrillation: A Prospective Randomized Clinical Study


Statins to prevent pacing-induced cardiomyopathy: Evidence from the bench applied to clinical studies


Dexmedetomidine versus propofol for operator-directed nurse-administered procedural sedation during catheter ablation of atrial fibrillation: A randomized controlled study


Efficacy of catheter ablation from the noncoronary aortic cusp of verapamil-sensitive atrial tachycardia arising near the atrioventricular node


Electrophysiological characteristics of septal perforation during left bundle branch pacing


Importance of newer cardiac magnetic resonance–based risk markers for sudden death prevention in hypertrophic cardiomyopathy: An international multicenter study


The evidence for the implantable loop recorder in patients with inherited arrhythmia syndromes: a review of the literature


Long-term outcomes in a randomized controlled trial of multimodality imaging-guided left ventricular lead placement in cardiac resynchronization therapy


Drug Interactions Affecting Oral Anticoagulant Use


02.06.2022: My Current Cardiology and AI Selection


Quality of Life after Fractional Flow Reserve–Guided PCI Compared With Coronary Bypass Surgery


Gliflozins in the Management of Cardiovascular Disease


Routine Removal of Inferior Vena Cava Filters


Long-term secondary prevention of cardiovascular disease with a Mediterranean diet and a low-fat diet (CORDIOPREV): a randomised controlled trial


Effect of a multi-domain lifestyle intervention on cardiovascular risk in older people: the FINGER trial


Cardiovascular Magnetic Resonance for Rejection Surveillance after Cardiac Transplantation


Effects of Long-term Metformin and Lifestyle Interventions on Cardiovascular Events in the Diabetes Prevention Program and Its Outcome Study


Electronic Alerts to Improve Heart Failure Therapy in Outpatient Practice: A Cluster Randomized Trial


Gender Differences in Takotsubo Syndrome


Disruption of Circadian Rhythms by Shift Work Exacerbates Reperfusion Injury in Myocardial Infarction


Prognostic Value of Time in Blood Pressure Target Range among Patients with Heart Failure


Acute Decompensated Heart Failure in the Setting of Acute Coronary Syndrome:

State-Of-The-Art Review


Artificial Intelligence:

Artificial intelligence and machine learning algorithms for early detection of skin cancer in community and primary care settings: a systematic review


Predicting hospitalisation for heart failure and death in patients with, or at risk of, heart failure before first hospitalisation: a retrospective model development and external validation study


Validation of the myocardial-ischaemic-injury-index machine learning algorithm to guide the diagnosis of myocardial infarction in a heterogenous population: a prespecified exploratory analysis


11.04.2022: My Current Cardiology and EP Selection



Tranexamic Acid in Patients Undergoing Noncardiac Surgery


Treatment for Mild Chronic Hypertension during Pregnancy


Deep learning-enabled coronary CT angiography for plaque and stenosis quantification and cardiac risk prediction: an international multicentre study


Effects of aspirin on dementia and cognitive function in diabetic patients: the ASCEND trial


Prevalence and Prognostic Implications of Left Ventricular Systolic Dysfunction in Adults with Congenital Heart Disease


Expert Consensus Statement on the state of genetic testing for cardiac diseases


Association of Cumulative Blood Pressure with Cognitive Decline, Dementia, and Mortality


2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure: A Report of the ACC/AHA Joint Committee on Clinical Practice Guidelines




Does Timing of Ventricular Tachycardia Ablation Affect Prognosis in Patients with an Implantable Cardioverter Defibrillator? Results From the Multicenter Randomized PARTITA Trial


Monogenic and Polygenic Contributions to QTc Prolongation in the Population


Measurement of Midregional Pro-Atrial Natriuretic Peptide to Discover Atrial Fibrillation in Patients with Ischemic Stroke


Management of ventricular tachycardia in patients with ischemic cardiomyopathy: contemporary armamentarium


EHRA consensus on prevention and management of interference due to medical procedures in patients with cardiac implantable electronic devices


How to use digital devices to detect and manage arrhythmias: an EHRA practical guide


Ectopy-triggering ganglionated plexuses ablation to prevent atrial fibrillation: GANGLIA-AF study


Empiric ablation of polymorphic ventricular tachycardia/fibrillation in the absence of a mappable trigger: Prospective feasibility and efficacy of pacemap matching to defibrillator electrograms


Cardiac deceleration capacity as an indicator for cardioneuroablation in patients with refractory vasovagal syncope


Lower body muscle preactivation and tensing mitigate symptoms of initial orthostatic hypotension in young females


Cardiac resynchronization therapy in patients with congenital heart disease and systemic right ventricle


30.03.2022: My Current Cardiology Selection

28.03.2022: My Current EP Selection

Restoring Sinus Rhythm Reverses Cardiac Remodeling and Reduces Valvular Regurgitation in Patients with Atrial Fibrillation


Lead-Related Venous Obstruction in Patients with Implanted Cardiac Devices: JACC Review Topic of the Week


Long-term monitoring of arrhythmias with cardiovascular implantable electronic devices in patients with cardiac sarcoidosis


Bradyarrhythmias detected by extended rhythm recording in patients undergoing transcatheter aortic valve replacement (Brady-TAVR Study)


High-density epicardial mapping in Brugada syndrome: Depolarization and repolarization abnormalities


Mechanism of the effects of sodium channel blockade on the arrhythmogenic substrate of Brugada syndrome


Multisite conduction block in the epicardial substrate of Brugada syndrome


Association Between Deleterious SCN5A Variants and Ventricular Septal Defect in Young Patients with Brugada Syndrome


Rate control drugs differ in the prevention of progression of atrial fibrillation


Antibiotic prophylaxis based on individual infective risk stratification in cardiac implantable electronic device: the PRACTICE study


Rate of device-related infections using an antibacterial envelope in patients undergoing cardiac resynchronization therapy reoperations.


Electrophysiology and Arrhythmogenesis in the Human Right Ventricular Outflow Tract


Orthostatic Hypotension: Management of a Complex, But Common, Medical Problem


Postmortem Interrogation of Cardiac Implantable Electronic Devices: A 15-Year Experience


16.03.2022: My Current Cardiology Selection

09.03.2022: My Current Cardiology Selection

22.02.2022: My current EP selection

18.02.2022: My current cardiology selection

21.01.2022: My current weekly selection



Miniseries 1—Part I: the Development of the atrioventricular conduction axis


Miniseries 1—Part II: the comparative anatomy of the atrioventricular conduction axis


Miniseries 1—Part III: ‘Behind the scenes’ in the triangle of Koch


Miniseries 1—Part IV: How frequent are fasciculo-ventricular connections in the normal heart?


Miniseries 2—septal and paraseptal accessory pathways—Part I: The anatomic basis for the understanding of para-Hisian accessory atrioventricular pathways


Miniseries 2—septal and paraseptal accessory pathways—part II: para-Hisian accessory pathways—so-called anteroseptal pathways revisited


Miniseries 2—septal and paraseptal accessory pathways—part III: mid-paraseptal accessory pathways—revisiting bypass tracts crossing the pyramidal space


Miniseries 2—septal and paraseptal accessory pathways—part IV: inferior paraseptal accessory pathways—lessons from surgical and catheter ablation


Leadless left ventricular stimulation with WiSE-CRT System – Initial experience and results from phase I of SOLVE-CRT Study (nonrandomized, roll-in phase)


European Society of Cardiology Quality Indicators for the care and outcomes of cardiac pacing: developed by the Working Group for Cardiac Pacing Quality Indicators in collaboration with the European Heart Rhythm Association of the European Society of Cardiology


2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy: Developed by the Task Force on cardiac pacing and cardiac resynchronization therapy of the European Society of Cardiology (ESC) with the special contribution of the European Heart Rhythm Association (EHRA)


12.01.2022: My current weekly selection

07.01.2022: My current weekly cardiology selection

05.01.2022: The year in cardiovascular medicine 2021

03.01.2022: My selection for Holidays, Part 2

Infectious consequences of hematoma from cardiac implantable electronic device procedures and the role of the antibiotic envelope: A WRAP-IT trial analysis


Lower rate limit for pacing by cardiac resynchronization defibrillators: Should lower rate programming be reconsidered?


Clinician needs and perceptions about cardioneuroablation for recurrent vasovagal syncope: An international clinician survey


Skin sympathetic nerve activity as a biomarker of fitness


Impact of High-Power Short-Duration Radiofrequency Ablation on Esophageal Temperature Dynamic


Brugada Syndrome: New Insights from Cardiac Magnetic Resonance and Electroanatomical Imaging


Understanding Circadian Mechanisms of Sudden Cardiac Death: A Report from the National Heart, Lung, and Blood Institute Workshop, Part 1: Basic and Translational Aspects


Understanding Circadian Mechanisms of Sudden Cardiac Death: A Report from the National Heart, Lung, and Blood Institute Workshop, Part 2: Population and Clinical Considerations


Safety/Efficacy of DOAC versus Aspirin for Reduction of Risk of Cerebrovascular Events Following VT Ablation


Using Machine-Learning for Prediction of the Response to Cardiac Resynchronization Therapy: The SMART-AV Study


Arrhythmias Utilizing Concealed Nodoventricular or His-Ventricular Pathways: A Structured Approach to Diagnosis and Management


P-Wave Morphology in Focal Atrial Tachycardia: An Updated Algorithm to Predict Site of Origin


Radiofrequency Energy Applications Targeting Significant Residual Leaks after Watchman Implantation: A Prospective, Multicenter Experience


Incidence of Device-Related Thrombosis in Watchman Patients Undergoing a Genotype-Guided Antithrombotic Strategy


Temporal Association of Atrial Fibrillation with Cardiac Implanted Electronic Device Detected Heart Failure Status


26.12.2021: My selection for Holidays, Part 1

22.12.2021: My selection from EHJ 

21.12.2021: My curent weekly selection


Association of Complement and MAPK Activation With SARS-CoV-2–Associated Myocardial Inflammation


2021 ACC/AHA/SCAI Guideline for Coronary Artery Revascularization: Executive Summary: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines


Machine Learning Approach to Classify Cardiovascular Disease in Patients With Nonalcoholic Fatty Liver Disease in the UK Biobank Cohort


Randomized Trial of Metoprolol in Patients With Obstructive Hypertrophic Cardiomyopathy


Effect of Mavacamten on Echocardiographic Features in Symptomatic Patients With Obstructive Hypertrophic Cardiomyopathy


Early Hospital Discharge Following PCI for Patients With STEMI



Temporal Association Between Episodes of Atrial Fibrillation and Risk of Ischemic Stroke


Medical therapies for prevention of cardiovascular and renal events in patients with atrial fibrillation and diabetes mellitus


Reconstituting electrical conduction in soft tissue: the path to replace the ablationist


Targeting non-pulmonary vein triggers in persistent atrial fibrillation: results from a prospective, multicentre, observational registry


Electrocardiographic characteristics and ablation of ventricular arrhythmias originating from the basal inferoseptal area


Epicardial ablation of ventricular tachycardia in patients with structural heart disease: a single-centre experience over 12 years


Driving Restrictions and Early Arrhythmias in Patients Receiving a Secondary Prevention Implantable Cardioverter-Defibrillator (DREAM-ICD-II study)


Mechanisms of Sinoatrial Node Dysfunction in Heart Failure with Preserved Ejection Fraction


Periodic Repolarization Dynamics Identifies ICD-responders in Non-ischemic Cardiomyopathy: A DANISH Substudy


16.12.2021: My curent weekly selection


Myocarditis after Covid-19 Vaccination in a Large Health Care Organization


Cardiovascular Events with Finerenone in Kidney Disease and Type 2 Diabetes


Edoxaban versus Vitamin K Antagonist for Atrial Fibrillation after TAVR


Triglyceride-rich lipoproteins and their remnants: metabolic insights, role in atherosclerotic cardiovascular disease, and emerging therapeutic strategies—a consensus statement from the European Atherosclerosis Society


Ticagrelor monotherapy in patients at high bleeding risk undergoing percutaneous coronary intervention: TWILIGHT-HBR


Cardiac mortality in patients randomised to elective coronary revascularisation plus medical therapy or medical therapy alone: a systematic review and meta-analysis


Exercise-Induced Cardiac Troponin Elevations: From Underlying Mechanisms to Clinical Relevance


Reduction in Acute Limb Ischemia With Rivaroxaban Versus Placebo in Peripheral Artery Disease After Lower Extremity Revascularization: Insights From VOYAGER PAD


Icosapent Ethyl Reduces Ischemic Events in Patients With a History of Previous Coronary Artery Bypass Grafting: REDUCE-IT CABG


Evaluating Medical Therapy for Calcific Aortic Stenosis: JACC State-of-the-Art Review

JACC State-Of-The-Art Review



AV junction ablation and cardiac resynchronization for patients with permanent atrial fibrillation and narrow QRS: the APAF-CRT mortality trial


Application of artificial intelligence to the electrocardiogram


Lower risk of stroke after alcohol abstinence in patients with incident atrial fibrillation: a nationwide population-based cohort study


Epigenetic Age and the Risk of Incident Atrial Fibrillation


Exercise-Induced Ventricular Ectopy and Cardiovascular Mortality in Asymptomatic Individuals


Longitudinal Oral Anticoagulant Adherence Trajectories in Patients With Atrial Fibrillation


Microcirculatory Resistance Predicts Allograft Rejection and Cardiac Events After Heart Transplantation


Substrate Characterization and Outcome of Catheter Ablation of Ventricular Tachycardia in Patients With Nonischemic Cardiomyopathy and Isolated Epicardial Scar


Shared Decision-Making in Cardiac Electrophysiology Procedures and Arrhythmia Management


Cardiac Resynchronization Therapy Response Is Equalized in Men and Women by Electrical Optimization: PR Matters


A Randomized Trial of His Pacing Versus Biventricular Pacing in Symptomatic HF Patients With Left Bundle Branch Block (His-Alternative)


Outcomes associated with pacemaker implantation following transcatheter aortic valve replacement: A nationwide cohort study


Permanent pacemaker implantation late after transcatheter aortic valve implantation


Three-year outcome after transcatheter aortic valve implantation: Comparison of a restrictive versus a liberal strategy for pacemaker implantation


Extracellular matrix remodeling precedes atrial fibrillation: Results of the PREDICT-AF trial


Recommendations regarding cardiac stereotactic body radiotherapy for treatment refractory ventricular tachycardia


02.05.2021, My April's Selection


Glycemic Index, Glycemic Load, and Cardiovascular Disease and Mortality


Empagliflozin Effects on Pulmonary Artery Pressure in Patients with Heart Failure

Results From the EMBRACE-HF Trial


Exercise Stress Real-Time Cardiac Magnetic Resonance Imaging for Noninvasive Characterization of Heart Failure with Preserved Ejection Fraction: The HFpEF-Stress Trial


Therapeutic Manipulation of Myocardial Metabolism: JACC State-of-the-Art Review


Patient Selection for Intensive Blood Pressure Management Based on Benefit and Adverse Events


Randomized Trial of Interleukin-6 Receptor Inhibition in Patients with Acute ST-Segment Elevation Myocardial Infarction


Effects of Fluoroquinolones on Outcomes of Patients with Aortic Dissection or Aneurysm


Thromboembolism in Heart Failure Patients in Sinus Rhythm: Epidemiology, Pathophysiology, Clinical Trials, and Future Direction



MicroRNA Biophysically Modulates Cardiac Action Potential by Direct Binding to Ion Channel


Relationship of LVEF and Myocardial Scar to Long-Term Mortality Risk and Mode of Death in Patients with Nonischemic Cardiomyopathy


Prognostic Value of Nonischemic Ringlike Left Ventricular Scar in Patients With Apparently Idiopathic Nonsustained Ventricular Arrhythmias


Marshall bundle elimination, Pulmonary vein isolation, and Line completion for ANatomical ablation of persistent atrial fibrillation (Marshall-PLAN): Prospective, single-center study


Temperature- and flow-controlled ablation/very-high-power short-duration ablation vs conventional power-controlled ablation: Comparison of focal and linear lesion characteristics


Systematic quantification of histologic ventricular fibrosis in isolated mitral valve prolapse and sudden cardiac death


Burst Exercise Testing Can Unmask Arrhythmias in Patients with Incompletely Penetrant Catecholaminergic Polymorphic Ventricular Tachycardia


Outcome of a Modified Sympathecotomy for Cardiac Neuromodulation of Untreatable Ventricular Tachycardia


Optimizing Impedance Change Measurement During Radiofrequency Ablation Enables More Accurate Characterization of Lesion Formation


Evolving Cardiac Electrical Therapies for Advanced Heart Failure Patients


02.03.2021, My papers' selection from the last two weeks:


Management of Antithrombotic Therapy after Acute Coronary Syndromes


Glycemic Index, Glycemic Load, and Cardiovascular Disease and Mortality


Finding new drugs for heart-valve disease: An artificial intelligence-enabled drug screen finds small molecules that can correct dysfunctional gene networks in aortic valve disease.


Utility of a Deep-Learning Algorithm to Guide Novices to Acquire Echocardiograms for Limited Diagnostic Use


Human Engineered Heart Tissue Patches Remuscularize the Injured Heart in a Dose-Dependent Manner


How Should We Sequence the Treatments for Heart Failure and a Reduced Ejection Fraction? A Redefinition of Evidence-Based Medicine


Prognostic Value of Coronary CT Angiography in Patients with Non–ST-Segment Elevation Acute Coronary Syndromes


Mitochondria-Rich Extracellular Vesicles from Autologous Stem Cell–Derived Cardiomyocytes Restore Energetics of Ischemic Myocardium


Does Patient-Physician Gender Concordance Influence Patient Perceptions or Outcomes? Cardiovascular Medicine and Society


Spironolactone in Patients with Heart Failure, Preserved Ejection Fraction, and Worsening Renal Function


Managing Patients with Short-Term Mechanical Circulatory Support: JACC Review Topic of the Week


How to Build an Antiracist Cardiovascular Culture, Community, and Profession: Cardiovascular Medicine and Society



Screening for Atrial Fibrillation in the Older Population: A Randomized Clinical Trial


Discovering and Visualizing Disease-Specific Electrocardiogram Features Using Deep Learning Proof-of-Concept in Phospholamban Gene Mutation Carriers


Circular Multielectrode Pulsed Field Ablation Catheter Lasso Pulsed Field Ablation

Lesion Characteristics, Durability, and Effect on Neighboring Structures


Does Pulsed Field Ablation Regress Over Time? A Quantitative Temporal Analysis of Pulmonary Vein Isolation


Oral Anticoagulants in Extremely High Risk Very Elderly (>90 years) Patients with Atrial Fibrillation


Arrhythmias and Device Therapies in Patients with Cancer Therapy-Induced Cardiomyopathy


Ventricular tachycardia burden reduction after substrate ablation: predictors of recurrence


Relationship between device-detected burden and duration of atrial fibrillation and risk of ischemic stroke


Reassessing the role of antitachycardia pacing in fast ventricular arrhythmias in primary prevention implantable cardioverter-defibrillator recipients: Results from MADIT-RIT


Active compression versus standard anterior-posterior defibrillation for external cardioversion of atrial fibrillation: A prospective randomized study


Epicardial course of the septopulmonary bundle: Anatomical considerations and clinical implications for roof line completion


18.02.2021, My papers' selection from the last two weeks:


Time to Clinical Benefit of Dapagliflozin and Significance of Prior Heart Failure Hospitalization in Patients with Heart Failure with Reduced Ejection Fraction


Sex-Related Differences in Cardiac Channelopathies: Implications for Clinical Practice


Coronary Optical Coherence Tomography and Cardiac Magnetic Resonance Imaging to Determine Underlying Causes of Myocardial Infarction with Nonobstructive Coronary Arteries in Women


Pathophysiology of Takotsubo Syndrome: JACC State-of-the-Art Review


Cardiac Involvement in Fabry Disease: JACC Review Topic of the Week


Pooled Analysis of PFO Occluder Device Trials in Patients with PFO and Migraine


Natriuretic Equation to Predict Loop Diuretic Response in Patients with Heart Failure


2021 Update to the 2017 ACC Expert Consensus Decision Pathway for Optimization of Heart Failure Treatment: Answers to 10 Pivotal Issues About Heart Failure with Reduced Ejection Fraction


Electrophysiology and Artificial Intelligence:

Magnetic Resonance Imaging in Patients with Cardiac Implantable Electronic Devices with Abandoned Lead


Use of Artificial Intelligence and Deep Neural Networks in Evaluation of Patients with Electrocardiographically Concealed Long QT Syndrome from the Surface 12-Lead Electrocardiogram


Deep Neural Networks Can Predict New-Onset Atrial Fibrillation From the 12-Lead Electrocardiogram and Help Identify Those at Risk of AF-Related Stroke


MicroRNA Biophysically Modulates Cardiac Action Potential via Directly Binding to Ion Channel


Association Between Sex and Treatment Outcomes of Atrial Fibrillation Ablation Versus Drug Therapy: Results from the CABANA Trial


Randomized Trial of Ivabradine in Patients with Hyperadrenergic Postural Orthostatic Tachycardia Syndrome


RBBB ventricular tachycardia in ARVC more commonly originates from the right ventricle: Criteria for identifying chamber of origin


Effect of pacemaker implantation after transcatheter aortic valve replacement on long- and mid-term mortality


Anticoagulation for stroke prevention in patients with hypertrophic cardiomyopathy and atrial fibrillation: A review


Left Bundle Branch Area Pacing for Cardiac Resynchronization Therapy: Results from the International LBBAP Collaborative Study Group


Efficiency of the RADPAD Surgical Cap in Reducing Brain Exposure During Pacemaker and Defibrillator Implantation


Concomitant Pulmonary Vein and Posterior Wall Isolation Using Cryoballoon With Adjunct Radiofrequency in Persistent Atrial Fibrillation


A Primary Prevention Clinical Risk Score Model for Patients With Brugada Syndrome (BRUGADA-RISK)


Fractionated Epicardial Electrograms: Implication for Mechanism of the Brugada Pattern: Global EP Rounds


02.02.2021, My papers' selection from the last two weeks:


An Electronically Delivered Patient-Activation Tool for Intensification of Medications for Chronic Heart Failure with Reduced Ejection Fraction


Research Priorities in Atrial Fibrillation Screening: A Report from a National Heart, Lung, and Blood Institute Virtual Workshop


Rivaroxaban Plus Aspirin in Obese and Overweight Patients with Vascular Disease in the COMPASS Trial


Mortality 10 Years After Percutaneous or Surgical Revascularization in Patients with Total Coronary Artery Occlusions


2020 ACC Expert Consensus Decision Pathway for Anticoagulant and Antiplatelet Therapy in Patients with Atrial Fibrillation or Venous Thromboembolism Undergoing Percutaneous Coronary Intervention or With Atherosclerotic Cardiovascular Disease.




Cryoablation or Drug Therapy for Initial Treatment of Atrial Fibrillation


Cryoballoon Ablation as Initial Therapy for Atrial Fibrillation


Digital Medical Tools for Heart Rhythm Professionals


Long-Term Outcomes in Patients with a Left Ejection Fraction ≤15% Undergoing Cardiac Resynchronization Therapy


Imaging-Based Localization of His Bundle Pacing Electrodes: Results from the Prospective IMAGE-HBP Study


Renal Denervation for the Management of Refractory Ventricular Arrhythmias: A Systematic Review


Renal Sympathetic Denervation as Upstream Therapy During Atrial Fibrillation Ablation: Pilot HFIB Studies and Meta-Analysis


Positive Clinical Benefit on Patient Care, Quality of Life, and Symptoms After Contact Force–Guided Radiofrequency Ablation in Persistent Atrial Fibrillation


The value of cardiac magnetic resonance imaging and programmed ventricular stimulation in patients with ventricular noncompaction and ventricular arrhythmias


Artificial Intelligence:


Ethical issues in using ambient intelligence in health-care settings


Rapid triage for COVID-19 using routine clinical data for patients attending hospital: development and prospective validation of an artificial intelligence screening test


Prediction of premature ventricular complex origins using artificial intelligence–enabled algorithms


12.01.2021, My VT papers' selection:

10.01.2021, My last week's selection:


Phase 3 Trial of Interleukin-1 Trap Rilonacept in Recurrent Pericarditis


Mortality with Paclitaxel-Coated Devices in Peripheral Artery Disease


Striking Similarities of Multisystem Inflammatory Syndrome in Children and a Myocarditis-Like Syndrome in Adults: Overlapping Manifestations of COVID-19


Icosapent-ethyl is the first non–low-density lipoprotein–lowering treatment that has been shown to reduce coronary artery bypass grafting in a blinded, randomized trial.



Primary Results From the Understanding Outcomes With the S-ICD in Primary Prevention Patients With Low Ejection Fraction (UNTOUCHED) Trial


Myocardial Fibrosis as a Predictor of Sudden Death in Patients With Coronary Artery Disease


Calcium-Induced Autonomic Denervation in Patients With Post-Operative Atrial Fibrillation


Left ventricular summit arrhythmias with an abrupt V3 transition: Anatomy of the aortic interleaflet triangle vantage point


Premature ventricular complex site of origin and ablation outcomes in patients with prior myocardial infarction


Risk of arrhythmic events after alcohol septal ablation for hypertrophic cardiomyopathy using continuous implantable cardiac monitoring


The rationale for repurposing funny current inhibition for management of ventricular arrhythmia


Artificial Intelligence:

Artificial intelligence for COVID-19: saviour or saboteur?


Predicting the risk of developing diabetic retinopathy using deep learning


Development and dissemination of infectious disease dynamic transmission models during the COVID-19 pandemic: what can we learn from other pathogens and how can we move forward?




Cardiac Pressure Overload Decreases ETV1 Expression in the Left Atrium, Contributing to Atrial Electrical and Structural Remodeling


The Diagnostic Value of Cardiac Deceleration Capacity in Vasovagal Syncope


Long-Term Evaluation of the Vagal Denervation by Cardioneuroablation using Holter and Heart Rate Variability


A pragmatic ablation approach targeting CMR-detected atrial fibrosis plus PVI was not more effective than PVI alone in an unselected population undergoing atrial fibrillation ablation with low fibrosis burden.


Novel Neuromodulation Approach to Improve Left Ventricular Contractility in Heart Failure


The Clinical Application of the Deep Learning Technique for Predicting Trigger Origins in Patients with Paroxysmal Atrial Fibrillation with Catheter Ablation


Cardiac Inflammation Impedes Response to Cardiac Resynchronization Therapy in Patients with Idiopathic Dilated Cardiomyopathy


Superior-Type Fast-Slow Atrioventricular Nodal Reentrant Tachycardia Phenotype Mimicking the Slow-Fast Type


Complex Re-Entrant Arrhythmias Involving the His-Purkinje System: A Structured Approach to Diagnosis and Management


Prevalence of Undiagnosed Sleep Apnea in Patients with Atrial Fibrillation and its Impact on Therapy


A Standardized and Comprehensive Approach to the Management of Cardiogenic Shock



Complete Hemodynamic Profiling with Pulmonary Artery Catheters in Cardiogenic Shock Is Associated with Lower In-Hospital Mortality


Polypill with or without Aspirin in Persons without Cardiovascular Disease


Sotagliflozin in Patients with Diabetes and Recent Worsening Heart Failure


Randomized Pilot Clinical Trial of Early Coronary Angiography Versus No Early Coronary Angiography After Cardiac Arrest Without ST-Segment Elevation: The PEARL Study


Prospective Multicenter Study of Myocardial Recovery Using Left Ventricular Assist Devices (RESTAGE-HF [Remission from Stage D Heart Failure])


Brain Injury After Transcatheter Replacement of Bicuspid Versus Tricuspid Aortic Valves


Gerotechnology for Older Adults with Cardiovascular Diseases: JACC State-of-the-Art Review


Cardiopulmonary Hemodynamics in Pulmonary Hypertension and Heart Failure: JACC Review Topic of the Week




Advanced Management of Intermediate- and High-Risk Pulmonary Embolism:

JACC Focus Seminar


Venous Thromboembolism Associated with Pregnancy: JACC Focus Seminar


Antithrombotic Management of Venous Thromboembolism: JACC Focus Seminar


Chronic Thromboembolic Pulmonary Hypertension: JACC Focus Seminar


Ventricular Tachycardia:

Intracardiac Impedance: A Novel Marker for Computed Tomography-Derived Wall Thinning in Ventricular Tachycardia Ablation


Safety and Outcomes of Ventricular Tachycardia Substrate Ablation During Sinus Rhythm: A Prospective Multicenter Registry


Intramural Venous Ethanol Infusion for Refractory Ventricular Arrhythmias: Outcomes of a Multicenter Experience


Modified Precordial Lead R-Wave Deflection Interval Predicts Left- and Right-Sided Idiopathic Outflow Tract Ventricular Arrhythmias


Increased Rate of Pump Thrombosis and Cardioembolic Events Following Ventricular Tachycardia Ablation in Patients Supported With Left Ventricular Assist Devices


Man vs machine: Performance of manual vs automated electrocardiogram analysis for predicting the chamber of origin of idiopathic ventricular arrhythmia


Signature signal strategy: Electrogram-based ventricular tachycardia mapping


Digital Health:

Digital health for primary prevention of cardiovascular disease: Promise to practice


A comprehensive artificial intelligence–enabled electrocardiogram interpretation program


Utilizing electronic health data and machine learning for the prediction of 30-day unplanned readmission or all-cause mortality in heart failure


Digital health innovation in cardiology



Drug-Induced Arrhythmias: A Scientific Statement from the American Heart Association


Arrhythmogenic Cardiomyopathy: A contemporary review of the history of arrhythmogenic cardiomyopathy highlighting the early discoverers and recent genetic work


Long-Term Follow-Up of Patients with Tetralogy of Fallot and Implantable Cardioverter Defibrillator: The DAI-T4F Nationwide Registry


In-hospital and long-term outcomes among patients with spontaneous coronary artery dissection presenting with ventricular tachycardia/fibrillation


Preimplantation inter-lead ECG heterogeneity is superior to QRS complex duration in predicting mechanical super-response in patients with non–left bundle branch block receiving cardiac resynchronization therapy


His-bundle and left bundle pacing with optimized atrioventricular delay achieve superior electrical synchrony over endocardial and epicardial pacing in left bundle branch block patients


Drivers of hospitalization in atrial fibrillation: A contemporary review


Percutaneous recanalization of superior vena cava occlusions for cardiac implantable electronic device implantation: Tools and techniques


Discriminating electrocardiographic responses to His-bundle pacing using machine learning



Colchicine in Patients with Chronic Coronary Disease


Association of Ticagrelor vs Clopidogrel With Net Adverse Clinical Events in Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention


Comparison Between Ticagrelor and Clopidogrel in Elderly Patients with an Acute Coronary Syndrome: Insights from the SWEDEHEART Registry


Deliberating the Diagnostic Dilemma of Heart Failure with Preserved Ejection Fraction


Evaluation and Management of Patients with Stable Angina: Beyond the Ischemia Paradigm: JACC State-of-the-Art Review




Effectiveness of Deep Sedation for Patients with Intractable Electrical Storm Refractory to Antiarrhythmic Drugs


Primary Results from the Understanding Outcomes with the S-ICD in Primary Prevention Patients with Low Ejection Fraction (UNTOUCHED) Trial


Exercise Training-Induced Repolarization Abnormalities Masquerading as Congenital Long QT Syndrome


Ablation of Atrial Fibrillation Without Left Atrial Appendage Imaging in Patients Treated with Direct Oral Anticoagulants


Complete Electroanatomic Imaging of the Diastolic Pathway Is Associated with Improved Freedom from Ventricular Tachycardia Recurrence


Flutter Wave Morphology of Peri-Mitral Atrial Flutters Is Mainly Determined by Right Atrial Activation: Insights from High-Resolution Mapping


Novel Cine-ECG Derived from Standard 12-Lead ECG Enables Right Ventricle Outflow Tract Localization of Electrical Substrate in Patients with Brugada Syndrome


Immunosuppressive Therapy and Risk Stratification of Patients With Myocarditis Presenting With Ventricular Arrhythmias


Para-Hisian Pacing During Sinus Rhythm: Establishing Threshold Values to Distinguish Nodal from Septal Pathway Conduction


Impact of Nonalcoholic Fatty Liver Disease on Arrhythmia Recurrence Following Atrial Fibrillation Ablation


Sudden cardiac arrest with shockable rhythm in patients with heart failure



NEJM, Clinical Practice: Secondary Mitral Regurgitation


Clinical Features and Outcomes of Pregnancy-Related Acute Aortic Dissection


Misclassification of Hospital Performance Under the Hospital Readmissions Reduction Program: Implications for Value-Based Programs


A randomized controlled trial of dapagliflozin on left ventricular hypertrophy in people with type two diabetes: the DAPA-LVH trial


Contemporary Diagnosis and Management of Rheumatic Heart Disease: Implications for Closing the Gap: A Scientific Statement From the American Heart Association


Effect of Pre-Hospital Crushed Prasugrel Tablets in Patients with STEMI Planned for Primary Percutaneous Coronary Intervention: The Randomized COMPARE CRUSH Trial


Left Ventricular Unloading is Associated with Lower Mortality in Cardiogenic Shock Patients Treated with Veno-Arterial Extracorporeal Membrane Oxygenation: Results from An International, Multicenter Cohort Study


Proteomic Signatures of Heart Failure in Relation to Left Ventricular Ejection Fraction


Structural Deterioration of Transcatheter Versus Surgical Aortic Valve Bioprostheses in the PARTNER-2 Trial


Molecular Imaging of Apoptosis in Atherosclerosis by Targeting Cell Membrane Phospholipid Asymmetry


Artificial Intelligence: 

Automated and partly automated contact tracing: a systematic review to inform the control of COVID-19


Chest x-ray analysis with deep learning-based software as a triage test for pulmonary tuberculosis: a prospective study of diagnostic accuracy for culture-confirmed disease




NEJM: Early Rhythm-Control Therapy in Patients with Atrial Fibrillation


Computerized Analysis of the Ventricular Fibrillation Waveform Allows Identification of Myocardial Infarction: A ProofofConcept Study for Smart Defibrillator Applications in Cardiac Arrest


Inflammation as a Predictor of Recurrent Ventricular Tachycardia After Ablation in Patients with Myocarditis


Automated electrocardiographic quantification of myocardial scar in patients undergoing primary prevention implantable cardioverter-defibrillator implantation: Association with mortality and subsequent appropriate and inappropriate therapies


Diagnostic yield and long-term outcome of nonischemic sudden cardiac arrest survivors and their relatives: Results from a tertiary referral center


Higher baseline cardiorespiratory fitness is associated with lower arrhythmia recurrence and death after atrial fibrillation ablation


Long-term outcomes of ventricular tachycardia substrate ablation incorporating hidden slow conduction analysis


Purkinje system hyperexcitability and ventricular arrhythmia risk in type 3 long QT syndrome


Electrocardiographic interpretation of pacemaker algorithms enabling minimal ventricular pacing


Use of virtual visits for the care of the arrhythmia patient



Five-Year Health Status After Self-expanding Transcatheter or Surgical Aortic Valve Replacement in High-risk Patients With Severe Aortic Stenosis


Rivaroxaban and Aspirin in Patients with Symptomatic Lower Extremity Peripheral Artery Disease


Angiotensin-Neprilysin Inhibition and Renal Outcomes in Heart Failure With Preserved Ejection Fraction


Diagnostic Yield of Electroanatomic Voltage Mapping in Guiding Endomyocardial Biopsies


Machine Learning Improves Cardiovascular Risk Definition for Young, Asymptomatic Individuals


Artificial Intelligence:

Reporting guidelines for clinical trial reports for interventions involving artificial intelligence: the CONSORT-AI extension


Guidelines for clinical trial protocols for interventions involving artificial intelligence: the SPIRIT-AI extension




Loss of SPEG Inhibitory Phosphorylation of Ryanodine Receptor Type-2 Promotes Atrial Fibrillation


Mortality in Patients with Atrial Fibrillation Receiving Nonrecommended Doses of Direct Oral Anticoagulants


Targeted Left Ventricular Lead Implantation Strategy for Non-Left Bundle Branch Block Patients: The ENHANCE CRT Study


RV Tissue Heterogeneity on CT: A Novel Tool to Identify the VT Substrate in ARVC


Prevalence and Prognostic Impact of Pathogenic Variants in Patients with Dilated Cardiomyopathy Referred for Ventricular Tachycardia Ablation


Are Contemporary Smartwatches and Mobile Phones Safe for Patients with Cardiovascular Implantable Electronic Devices?


Multicenter Study of Dynamic High-Density Functional Substrate Mapping Improves Identification of Substrate Targets for Ischemic Ventricular Tachycardia Ablation


Strategies for Catheter Ablation of Left Ventricular Papillary Muscle Arrhythmias

An Institutional Experience


Initial Experience, Safety, and Feasibility of Left Bundle Branch Area Pacing

A Multicenter Prospective Study



Association between high blood pressure and long-term cardiovascular events in young adults: systematic review and meta-analysis


Effect of Clopidogrel and Aspirin vs Aspirin Alone on Migraine Headaches After Transcatheter Atrial Septal Defect Closure: One-Year Results of the CANOA Randomized Clinical Trial


Fractional flow reserve in clinical practice: from wire-based invasive measurement to image-based computation


Artificial Intelligence to measure coronary artery flow


Automated Recognition of Regional Wall Motion Abnormalities Through Deep Neural Network Interpretation of Transthoracic Echocardiography


Intracranial Arterial Calcification: Prevalence, Risk Factors, and Consequences




Impact of Left Ventricular Function and Heart Failure Symptoms on Outcomes Post Ablation of Atrial Fibrillation in Heart Failure: CASTLE-AF Trial


Long-Term Outcome in High-Risk Patients with Hypertrophic Cardiomyopathy after Primary Prevention Defibrillator Implants


Pulmonary Vein Isolation with Single Pulse Irreversible Electroporation: A First in Human Study in 10 Patients with Atrial Fibrillation


Power, Lesion Size Index and Oesophageal Temperature Alerts during Atrial Fibrillation Ablation: A Randomized Study


An International Multicenter Evaluation of Inheritance Patterns, Arrhythmic Risks, and Underlying Mechanisms of CASQ2-Catecholaminergic Polymorphic Ventricular Tachycardia


Association of Autoimmune Vasculitis and Incident Atrial Fibrillation: A PopulationBased CaseControl Study


High-resolution, live, directional mapping



Multimodality Imaging in Evaluation of Cardiovascular Complications in Patients With COVID-19: JACC Scientific Expert Panel


Altered Hemodynamics and End-Organ Damage in Heart Failure

Impact on the Lung and Kidney


Current Evidence and Recommendations for Coronary CTA First in Evaluation of Stable Coronary Artery Disease


Nonculprit Lesion Severity and Outcome of Revascularization in Patients with STEMI and Multivessel Coronary Disease


Short-term and Long-term Feasibility, Safety, and Efficacy of High-Intensity Interval Training in Cardiac Rehabilitation


Artificial Intelligence:

Effect of artificial intelligence-based triaging of breast cancer screening mammograms on cancer detection and radiologist workload: a retrospective simulation study


Artificial intelligence in medical imaging: switching from radiographic pathological data to clinically meaningful endpoints


The myth of generalisability in clinical research and machine learning in health care




Risk of Arrhythmic Events Following Alcohol Septal Ablation for Hypertrophic Cardiomyopathy Using Continuous Implantable Cardiac Monitoring


Predictors of long-term mortality after catheter ablation of ventricular tachycardia in a contemporary cohort of patients with structural heart disease


Epicardial Adipose Tissue Accumulation Confers Atrial Conduction Abnormality


Significance of fragmented QRS complexes for predicting new-onset atrial fibrillation after cavotricuspid isthmus–dependent atrial flutter ablation


Acute and long-term results of bipolar radiofrequency catheter ablation of refractory ventricular arrhythmias of deep intramural origin


Anatomic approach with bipolar ablation between the left pulmonic cusp and left ventricular outflow tract for left ventricular summit arrhythmias


Percutaneous approaches for retrieval of an embolized or malpositioned left atrial appendage closure device: A multicenter experience


Axillary vein puncture guided by ultrasound vs cephalic vein dissection in pacemaker and defibrillator implant: A multicenter randomized clinical trial


Modern mapping and ablation techniques to treat ventricular arrhythmias from the left ventricular summit and interventricular septum



Cardiovascular and Renal Outcomes with Empagliflozin in Heart Failure


Atherosclerotic Plaque Healing


The Effect of Adding Ticagrelor to Standard Aspirin on Saphenous Vein Graft Patency in Patients Undergoing Coronary Artery Bypass Grafting (POPular CABG): A Randomized, Double-Blind, Placebo-Controlled Trial


Renal and Cardiovascular Effects of SGLT2 Inhibition in Combination with Loop Diuretics in Patients with Type 2 Diabetes and Chronic Heart Failure: The RECEDE-CHF Trial


Coronary Computed Tomography Angiography from Clinical Uses to Emerging Technologies


In patients with multivessel CAD and diabetes, CABG was associated with improved long-term mortality and freedom from MACCEs compared with PCI.



Weekly Best Selection:


Atrial Arrhythmias in Clinically Manifest Cardiac Sarcoidosis: Incidence, Burden, Predictors, and Outcomes


Machine Learning to Classify Intracardiac Electrical Patterns During Atrial Fibrillation


Long-Term Outcome After Ventricular Tachycardia Ablation in Nonischemic Cardiomyopathy


Efficacy of an Adjunctive Electrophysiological Test–Guided Left Atrial Posterior Wall Isolation in Persistent Atrial Fibrillation Without a Left Atrial Low-Voltage Area


Bilateral Bundle Branch Area Pacing to Achieve Physiological Conduction System Activation


Impact of High-Power Short-Duration Radiofrequency Ablation on Long-Term Lesion Durability for Atrial Fibrillation Ablation



General versus Local Anesthesia with Conscious Sedation in Transcatheter Aortic Valve Implantation: The Randomized SOLVE-TAVI Trial


Stress Myocardial Perfusion Imaging vs Coronary Computed Tomographic Angiography for Diagnosis of Invasive Vessel-Specific Coronary Physiology


Feasibility of using deep learning to detect coronary artery disease based on facial photo


Improved cardiovascular risk prediction using targeted plasma proteomics in primary prevention


Pulmonary Artery Denervation for Patients with Residual Pulmonary Hypertension After Pulmonary Endarterectomy


Imaging of Clinically Unrecognized Myocardial Fibrosis in Patients with Suspected Coronary Artery Disease


Machine Learning Assessment of Left Ventricular Diastolic Function Based on Electrocardiographic Features




Integrated management of atrial fibrillation in primary care: results of the ALL-IN cluster randomized trial


An autoantibody profile detects Brugada syndrome and identifies abnormally expressed myocardial proteins


Impact of interruptions in radiofrequency energy delivery on lesion characteristics: These data suggest that if disruption in energy delivery occurs, lesions may need closer spacing to avoid gaps.


An Artificial Intelligence-Enabled ECG Algorithm to Identify Patients with Left Ventricular Systolic Dysfunction Presenting to the Emergency Department with Dyspnea: 

The AUC, accuracy, sensitivity, and specificity were 0.85 (95% CI: 0.83 - 0.88), 86%, 63%, and 91%, respectively.


Esophageal Endoscopy After Catheter Ablation of Atrial Fibrillation Using Ablation-Index Guided High-Power


Targeted Left Ventricular Lead Implantation Strategy for Non-Left Bundle Branch Block Patients


Worse Prognosis in Brugada Syndrome Patients with Arrhythmogenic Cardiomyopathy Features: The right ventricular outflow tract dilation criterion improved detection of arrhythmic BrS patients.



Cost-effectiveness of Sacubitril-Valsartan in Hospitalized Patients Who Have Heart Failure with Reduced Ejection Fraction


Built Environment Approaches to Increase Physical Activity: A Science Advisory from the American Heart Association


Long-Term Adverse Cardiac Outcomes in Patients with Sarcoidosis


Optimum Blood Pressure in Patients with Shock After Acute Myocardial Infarction and Cardiac Arrest


Heart Failure with Recovered Left Ventricular Ejection Fraction

JACC Scientific Expert Panel


Role of Cardiac Lymphatics in Myocardial Edema and Fibrosis

JACC Review Topic of the Week


Transvalvular Ventricular Unloading Before Reperfusion in Acute Myocardial Infarction






Evaluation of Stress Cardiac Magnetic Resonance Imaging in Risk Reclassification of Patients with Suspected Coronary Artery Disease


Randomized Trials Versus Common Sense and Clinical Observation

JACC Review Topic of the Week


Targeting RNA With Antisense Oligonucleotides and Small Interfering RNA

JACC State-of-the-Art Review


2020 ACC Expert Consensus Decision Pathway on Management of Bleeding in Patients on Oral Anticoagulants


Effect of Sacubitril/Valsartan on Biomarkers of Extracellular Matrix Regulation in Patients with HFpEF


Transcatheter Valve-in-Valve Aortic Valve Replacement as an Alternative to Surgical Re-Replacement


Penetrance of Hypertrophic Cardiomyopathy in Sarcomere Protein Mutation Carriers



Sex-specific efficacy and safety of cryoballoon versus radiofrequency ablation for atrial fibrillation: An individual patient data meta-analysis


Stereotactic arrhythmia radioablation for refractory scar-related ventricular tachycardia


Novel risk calculator performance in athletes with arrhythmogenic right ventricular cardiomyopathy


Periaortic ventricular tachycardia in structural heart disease: Evidence of localized reentrant mechanisms


Usefulness of positive T wave in lead aVR in predicting arrhythmic events and mortality in patients with hypertrophic cardiomyopathy


Atrial tachycardia eliminated at the ventricular side in patients with congenitally corrected transposition of the great arteries: Electrophysiological findings and anatomical concerns




Association of Low-Dose Triple Combination Therapy with Therapeutic Inertia and Prescribing Patterns in Patients with Hypertension: A Secondary Analysis of the TRIUMPH Trial


Association of Natriuretic Peptide Levels After Transcatheter Aortic Valve Replacement with Subsequent Clinical Outcomes


Pathogenic Autoimmunity in Atherosclerosis Evolves from Initially Protective ApoB-Reactive CD4+ T-Regulatory Cells


The Expected 30-year Benefits of Early Versus Delayed Primary Prevention of Cardiovascular Disease by Lipid Lowering


Pathophysiology and Acute Management of Tachyarrhythmias in Pheochromocytoma



Comparison of Atrial Remodeling Caused by Sustained Atrial Flutter Versus Atrial Fibrillation


Long-Term Outcomes of Implantable Cardioverter-Defibrillator Therapy in the SCD-HeFT


Inhibition of Human Ether-A-Go-Go-Related Gene (hERG) Potassium Current by the Novel Sotalol Analogue, Soestalol


Frequency Content of Unipolar Electrograms May Predict Deep Intramural Excitable Substrate


Acute Hemoptysis Following Cryoballoon Pulmonary Vein Isolation


High-Density Characterization of the Ventricular Electrical Substrate During Sinus Rhythm in Post–Myocardial Infarction Patients


Characterization of Complex Atrial Tachycardia in Patients with Previous Atrial Interventions Using High-Resolution Mapping


Cardiac Resynchronization Therapy in Patients with Nonischemic Cardiomyopathy Using Left Bundle Branch Pacing


Electrocardiographic Analysis for His Bundle Pacing at Implantation and Follow-Up












Machine Learning in EP:

Pre-Procedure Application of Machine Learning and Mechanistic Simulations Predicts Likelihood of Paroxysmal Atrial Fibrillation Recurrence Following Pulmonary Vein Isolation


Machine Learning of 12-lead QRS Waveforms to Identify Cardiac Resynchronization Therapy Patients with Differential Outcomes


Prospective Assessment of An Automated Intraprocedural 12-lead ECG-Based System for Localization of Early Left Ventricular Activation



Residual inflammatory risk associated with interleukin-18 and interleukin-6 after successful interleukin-1β inhibition with canakinumab: further rationale for the development of targeted anti-cytokine therapies for the treatment of atherothrombosis


The cardiac sympathetic co-transmitter neuropeptide Y is pro-arrhythmic following ST-elevation myocardial infarction despite beta-blockade


Chronic infarct size after spontaneous coronary artery dissection: implications for pathophysiology and clinical management


Clinical application of the 4th Universal Definition of Myocardial Infarction


Ventricular Arrhythmias: 

Evaluation of Radiofrequency Ablation Irrigation Type: In Vivo Comparison of Normal Versus Half-Normal Saline Lesion Characteristics


Electroanatomical Voltage Mapping to Distinguish Right-Sided Cardiac Sarcoidosis from Arrhythmogenic Right Ventricular Cardiomyopathy


Right Ventricular Electrogram Characteristics in a T1 Mapping-Validated Normal Population: Implications for Unipolar Voltage Mapping


Risk Stratification of Patients with Apparently Idiopathic Premature Ventricular Contractions: A Multicenter International CMR Registry


Idiopathic Ventricular Fibrillation: Role of Purkinje System and Microstructural Myocardial Abnormalities







Drug-Coated Balloon Angioplasty Versus Drug-Eluting Stent Implantation in Patients with Coronary Stent Restenosis


Two thirds of patients aged > 80 years with hypertension maintained blood pressure control for 12 weeks with one fewer antihypertensive medication.


The Unrecognized Prevalence of Primary Aldosteronism



Prevalence and clinical impact of spontaneous and adenosine-induced pulmonary vein reconduction in the Contact-Force vs. Cryoballoon Atrial Fibrillation Ablation (CIRCA-DOSE) study


Effect of acute myocardial ischemia on inferolateral early repolarization


Ventricular-triggered atrial pacing: A new maneuver for slow-fast atrioventricular nodal reentrant tachycardia


The role of long noncoding RNAs in atrial fibrillation


Ventricular Arrhythmias:

Long-term Outcomes of Ventricular Tachycardia Substrate Ablation Incorporating Hidden Slow Conduction Analysis


An electrocardiographic sign of idiopathic ventricular tachycardia ablatable from the distal great cardiac vein


Automated Electrocardiographic Quantification of Myocardial Scar in Patients Undergoing Primary Prevention Implantable Cardioverter Defibrillator Implantation: Association with Mortality and Subsequent Appropriate and Inappropriate Therapies


QRS Morphology in Lead V1 for the Rapid Localization of Idiopathic Ventricular Arrhythmias Originating from The Left Ventricular Papillary Muscles: A Novel Electrocardiographic Criterion


Purkinje System Hyperexcitability and Ventricular Arrhythmia Risk in Type 3 Long QT Syndrome



A novel nine-partition method using fluoroscopic images for guiding left bundle branch pacing


Safety and Efficacy of Leadless Pacemaker for Cardio Inhibitory Vasovagal Syncope


Algorithm for the analysis of pre-extraction computed tomographic images to evaluate implanted lead–lead interactions and lead–vascular attachments

















A Simplified Proposal to Redefine Acute Myocardial Infarction Versus Acute Myocardial Injury


Ten-Year Outcomes After Drug-Eluting Stents Versus Coronary Artery Bypass Grafting for Left Main Coronary Disease


Long-term ticagrelor for secondary prevention in patients with prior myocardial infarction and no history of coronary stenting: insights from PEGASUS-TIMI 54


Fractional flow reserve in patients with reduced ejection fraction


High-Sensitivity Cardiac Troponin I Levels and Prediction of Heart Failure


Long-term transesophageal echocardiography follow-up after percutaneous left atrial appendage closure



Pulsed-Field Ablation Using a Lattice Electrode for Focal Energy Delivery: Biophysical Characterization, Lesion Durability and Safety Evaluation


Ablation of Reentry-Vulnerable-Zones Determined by Left Ventricular Activation from Multiple Directions: A Novel Approach for Ventricular Tachycardia Ablation: A Multicenter Study (PHYSIO-VT)


Focal Pulsed Field Ablation for Pulmonary Vein Isolation and Linear Atrial Lesions: A Preclinical Assessment of Safety and Durability


Impact of Cardiac Resynchronization Therapy on Heart Transplant–Free Survival in Pediatric and Congenital Heart Disease Patients


Relation of Fractionated Atrial Potentials with the Vagal Innervation Evaluated by Extracardiac Vagal Stimulation During Cardioneuroablation


Device-Pocket Hematoma After Cardiac Implantable Electronic Devices


Review: Left Bundle Branch Block



Among patients in underserved countries who received a resterilized and reused pacemaker or defibrillator, the incidence of infection or device-related death at 2 years was 2.0%, an incidence that did not differ significantly from that seen among matched control patients with new devices in Canada.







The Prognostic Significance of Quantitative Myocardial Perfusion an Artificial Intelligence–Based Approach Using Perfusion Mapping


Exercise and Coronary Atherosclerosis

Observations, Explanations, Relevance, and Clinical Management


Lifestyle and Risk Factor Modification for Reduction of Atrial Fibrillation: A Scientific Statement from the American Heart Association


The ISCHEMIA Trial: Was it Worth the Wait?


Lipid-Modifying Agents, From Statins to PCSK9 Inhibitors

JACC Focus Seminar


Diabetic Agents, From Metformin to SGLT2 Inhibitors and GLP1 Receptor Agonists

JACC Focus Seminar


Complement C5 Protein as a Marker of Subclinical Atherosclerosis


Successful Oral Step-Down Endocarditis Treatment Affirmed




Atrial fibrillation in Brugada syndrome: Current perspectives


Heterogeneity in Conduction Underlies Obesity Related Atrial Fibrillation Vulnerability


Mapping After Pulmonary Vein Isolation in Persistent Atrial Fibrillation: Insights into the Role of Focal and Rotational Activation during Atrial Fibrillation


Ablation of Supraventricular Tachycardias From Concealed Left-sided Nodoventricular And Nodofascicular Accessory Pathways


Ventricular Tachycardia:


Irrigated Microwave Catheter Ablation Can Create Deep Ventricular Lesions Through Epicardial Fat with Relative Sparing of Adjacent Coronary Arteries


Catheter Ablation in Patients with Cardiogenic Shock and Refractory Ventricular Tachycardia


Ablation at Right Coronary Cusp as an Alternative and Favorable Approach to Eliminate Premature Ventricular Complexes Originating from the Proximal Left Anterior Fascicle






Research Priorities for Heart Failure with Preserved Ejection Fraction

National Heart, Lung, and Blood Institute Working Group Summary


Rivaroxaban Plus Aspirin Versus Aspirin Alone in Patients with Prior Percutaneous Coronary Intervention (COMPASS-PCI)


Value of Hemodynamic Monitoring in Patients with Cardiogenic Shock Undergoing Mechanical Circulatory Support


Short-Term Progression of Multiterritorial Subclinical Atherosclerosis


Antithrombotic Therapy for Patients with Left Ventricular Mural Thrombus


Novel Devices in Heart Failure

BAT, Atrial Shunts, and Phrenic Nerve Stimulation



Multicenter Emergency Department Validation of the Canadian Syncope Risk Score


Anticoagulation-Related Major Bleeding in Patients with Atrial Fibrillation

Looking Behind the Curtain


The role of genetics in cardiovascular disease: arrhythmogenic cardiomyopathy


High penetrance and similar disease progression in probands and in family members with arrhythmogenic cardiomyopathy


Arrhythmogenic right ventricular cardiomyopathy: evidence for progression increases


Arrhythmogenic right ventricular cardiomyopathy: evaluation of the current diagnostic criteria and differential diagnosis


Cardiovascular magnetic resonance imaging volume criteria for arrhythmogenic right ventricular cardiomyopathy: need for update?


Right ventricular dilatation in arrhythmogenic right ventricular cardiomyopathy: need for a revision of the 2010 International Task Force criteria


Atrial Fibrillation

JACC Council Perspectives






Official Hypertension Recommendations Might Not Apply to Most Patients


Antihypertension Medications Might Best Be Taken at Night


Effect of salt substitution on community-wide blood pressure and hypertension incidence


Intravenous Statin Administration During Myocardial Infarction Compared with Oral Post-Infarct Administration



How Effective Are Atrial Fibrillation Detection Strategies?


Pulsed Field Ablation Versus Radiofrequency Ablation

Esophageal Injury in a Novel Porcine Model


Automated Noncontact Ultrasound Imaging and Ablation System for the Treatment of Atrial Fibrillation


A Population-Based Study Evaluating Sex Differences in Patients Presenting to Emergency Departments with Syncope


Sudden cardiac death risk prediction in heart failure with preserved ejection fraction


Stereotactic arrhythmia radioablation for refractory scar-related ventricular tachycardia


'Cardiac Radioablation – a Systematic Review′


Prognostic Implication of FirstDegree Atrioventricular Block in Patients with Hypertrophic Cardiomyopathy


Artificial Intelligence and Digital Health:

Deep Learning–Based Algorithm for Detecting Aortic Stenosis Using Electrocardiography


Early prediction of circulatory failure in the intensive care unit using machine learning


Assessing and Mitigating Bias in Medical Artificial Intelligence

The Effects of Race and Ethnicity on a Deep Learning Model for ECG Analysis


Skin-interfaced biosensors for advanced wireless physiological monitoring in neonatal and pediatric intensive-care units





In hospitalized adult patients with severe Covid-19, no benefit was observed with lopinavir–ritonavir treatment beyond standard care



Heart Failure Management Innovation Enabled by Electronic Health Records


Contribution of income and job strain to the association between education and cardiovascular disease in 1.6 million Danish employees


Rivaroxaban Plus Aspirin Versus Aspirin Alone in Patients with Prior Percutaneous Coronary Intervention (COMPASS-PCI)


Improved Survival with Extracorporeal Cardiopulmonary Resuscitation Despite Progressive Metabolic Derangement Associated with Prolonged Resuscitation


Inflammation in Heart Failure


Select Drug-Drug Interactions With Direct Oral Anticoagulants


Multiple Plasma Biomarkers for Risk Stratification in Patients With Heart Failure and Preserved Ejection Fraction


Oral Anticoagulation and Cardiovascular Outcomes in Patients With Atrial Fibrillation and End-Stage Renal Disease



Relation of Fractionated Atrial Potentials with the Vagal Innervation Evaluated by Extracardiac Vagal Stimulation during Cardioneuroablation


Accumulation of Pericardial Fat Is Associated with Alterations in Heart Rate Variability Patterns in Hypercholesterolemic Pigs


Accurate Conduction Velocity Maps and their Association with Scar Distribution on Magnetic Resonance Imaging in Patients with Post-Infarction Ventricular Tachycardias


Left Bundle Branch Block: Current and Future Perspectives


Diagnosis-to-Ablation Time and Recurrence of Atrial Fibrillation Following Catheter Ablation: A Systematic Review and Meta-analysis of Observational Studies


Substrate Spatial Complexity Analysis for the Prediction of Ventricular Arrhythmias in Patients with Ischemic Cardiomyopathy


The Atrium and Embolic Stroke

Myopathy Not Atrial Fibrillation as the Requisite Determinant?


Esophageal Thermal Injury Following Cryoballoon Ablation for Atrial Fibrillation


Risk Prediction Model for Cardiac Implantable Electronic Device Implantation After Transcatheter Aortic Valve Replacement


Mortality Risk Increases With Clustered Ventricular Arrhythmias in Patients With Implantable Cardioverter-Defibrillators








Unfolding Discoveries in Heart Failure: Three ways to Break his Heart


Polymer-based or Polymer-free Stents in Patients at High Bleeding Risk


Prognostic Implications of Discordant Electrocardiogram and Imaging on Stress Echocardiography


Menopause-Related Estrogen Decrease and the Pathogenesis of HFpEF



For People with Lamin-A/C Mutations, Long-Term Exercise Might Worsen Dilated Cardiomyopathy


Electrical versus pharmacological cardioversion for emergency department patients with acute atrial fibrillation (RAFF2): A partial factorial randomized trial


Using Routine Cardiac MRI vs. Echocardiography (with Selective MRI) in Nonischemic Heart Failure: Which Strategy is Better?


Effectiveness of Implanted Cardiac Rhythm Recorders with Electrocardiographic Monitoring for Detecting Arrhythmias in Pregnant Women with Symptomatic Arrhythmia and/or Structural Heart Disease


Sudden cardiac death risk prediction in heart failure with preserved ejection fraction


Ventricular Arrhythmias:

Standard peak-to-peak bipolar voltage amplitude criteria underestimate myocardial scar during substrate mapping with a novel microelectrode catheter


Direct and indirect mapping of intramural space in ventricular tachycardia


Simple electrocardiographic criteria for rapid identification of wide QRS complex tachycardia: The new limb lead algorithm


Risk stratification in patients with frequent premature ventricular complexes in the absence of known heart disease


Clinical experience of stereotactic body radiation for refractory ventricular tachycardia in advanced heart failure patients


Ventricular arrhythmia risk prediction in repaired Tetralogy of Fallot using personalized computational cardiac models


Characteristics of myocardial tissue staining and lesion creation with an infusion-needle ablation catheter for the treatment of ventricular tachycardia in humans


Ventricular Arrhythmias in Myocarditis: Characterization and Relationships with Myocardial Inflammation






Which Mechanical Circulatory Support Device for Patients with Myocardial Infarction and Cardiovascular Shock?


Diagnosis and Treatment of Fulminant Myocarditis


Long-term Outcomes Associated with Total Arterial Revascularization vs Non–Total Arterial Revascularization


Machine Learning Framework to Identify Individuals at Risk of Rapid Progression of Coronary Atherosclerosis: From the PARADIGM Registry


Intravascular Ultrasound Imaging–Guided Versus Coronary Angiography–Guided Percutaneous Coronary Intervention: A Systematic Review and MetaAnalysis



Elimination of modifiable bleeding risk factors is a potentially effective strategy to reduce bleeding risk in atrial fibrillation patients receiving rivaroxaban


Association of Left Atrial High-Resolution Late Gadolinium Enhancement on Cardiac Magnetic Resonance with Electrogram Abnormalities Beyond Voltage in Patients with Atrial Fibrillation


Protein Biomarkers and Risk of Atrial Fibrillation


Evaluation of ECG Imaging to Map Hemodynamically Stable and Unstable Ventricular Arrhythmias


Impedance in the Diagnosis of Lead Malfunction


Strategies to Improve Selection of Patients Without Typical Left Bundle Branch Block for Cardiac Resynchronization Therapy


Evaluating Electrocardiography-Based Identification of Cardiac Resynchronization Therapy Responders Beyond Current Left Bundle Branch Block Definitions


Follow-Up After Myocardial Infarction to Explore the Stability of Arrhythmogenic Substrate


Trends in Successful Ablation Sites and Outcomes of Ablation for Idiopathic Outflow Tract Ventricular Arrhythmias


Non–Scar-Related and Purkinje-Related Ventricular Tachycardia in Patients With Structural Heart Disease


Man, versus machine: Performance of manual vs automated electrocardiogram analysis for predicting the chamber of origin of idiopathic ventricular arrhythmia














In Depth: Regulatory RNAs in Heart Failure


Reevaluating the Genetic Contribution of Monogenic Dilated Cardiomyopathy


Utilization and Outcomes of Measuring Fractional Flow Reserve in Patients with Stable Ischemic Heart Disease


Left Ventricular Post-Infarct Remodeling: Implications for Systolic Function Improvement and Outcomes in the Modern Era


Durability and Efficacy of Tricuspid Valve Repair in Patients Undergoing Left Ventricular Assist Device Implantation


Advanced Heart Failure in Adults with Congenital Heart Disease


Association of Clinical Outcomes with Left Ventricular Assist Device Use by Bridge to Transplant or Destination Therapy Intent



Percutaneous Epicardial Approach to Catheter Ablation of Cardiac Arrhythmias


Incidence of Left Atrial Appendage Triggers in Patients with Atrial Fibrillation Undergoing Catheter Ablation


Focal Ventricular Tachycardias in Structural Heart Disease

Prevalence, Characteristics, and Clinical Outcomes After Catheter Ablation


Circulating miRNAs and Risk of Sudden Death in Patients with Coronary Heart Disease


Atrioventricular Synchronous Pacing Using a Leadless Ventricular Pacemaker

Results from the MARVEL 2 Study


Venous Vascular Closure System Versus Manual Compression Following Multiple Access Electrophysiology Procedures: The AMBULATE Trial


Functional Atrial Endocardial–Epicardial Dissociation in Patients with Structural Heart Disease Undergoing Cardiac Surgery


Short-Term Hemodynamic and Electrophysiological Effects of Cardiac Resynchronization by Left Ventricular Septal Pacing


Left Ventricular Septal Versus Left Bundle Branch Pacing

A New Beginning in Cardiac Resynchronization Therapy?





High-Sensitivity Cardiac Troponin and the Universal Definition of Myocardial Infarction


LDL-Cholesterol Lowering Strategies and Population Health - Time to Move to a Cumulative Exposure Model


Natural Compound Library Screening Identifies New Molecules for the Treatment of Cardiac Fibrosis and Diastolic Dysfunction


JACC Review Topic of the Week: Embolic Stroke of Undetermined Source


Morphine and Cardiovascular Outcomes Among Patients with Non-ST-Segment Elevation Acute Coronary Syndromes Undergoing Coronary Angiography



Oral Anticoagulation for Patients with Atrial Fibrillation on Long-Term Hemodialysis


Characterization of Structural Changes in Arrhythmogenic Right Ventricular Cardiomyopathy with Recurrent Ventricular Tachycardia After Ablation: Insights from Repeat Electroanatomic Voltage Mapping


Epicardial Connections Involving Pulmonary Veins

The Prevalence, Predictors, and Implications for Ablation Outcome


Differentiating Atrioventricular Reentry Tachycardia and Atrioventricular Node Reentry Tachycardia Using Premature His Bundle Complexes


Higher Incidence of Asymptomatic Cerebral Emboli After Atrial Fibrillation Ablation Found with High-Resolution Diffusion-Weighted Magnetic Resonance Imaging


Effect of Renal Denervation and Catheter Ablation vs Catheter Ablation Alone on Atrial Fibrillation Recurrence Among Patients with Paroxysmal Atrial Fibrillation and Hypertension: The ERADICATE-AF Randomized Clinical Trial




First in Human Experience with Peritoneal Direct Sodium Removal Using a Zero Sodium Solution: A New Candidate Therapy for Volume Overload


Peripartum Cardiomyopathy: JACC State-of-the-Art Review


Atrial Failure as a Clinical Entity: JACC Review Topic of the Week


Long-term outcomes of chronic coronary syndrome worldwide: insights from the international CLARIFY registry


How should we manage risks associated with chronic coronary syndromes?


Machine learning of clinical variables and coronary artery calcium scoring for the prediction of obstructive coronary artery disease on coronary computed tomography angiography: analysis from the CONFIRM registry


Development and validation of a ceramide- and phospholipid-based cardiovascular risk estimation score for coronary artery disease patients


Relationship between coronary plaque morphology of the left anterior descending artery and 12 months clinical outcome: the CLIMA study


The year in cardiology: coronary interventions: The year in cardiology 2019


Operator Experience and Outcomes of Transcatheter Mitral Valve Repair in the United States



Incidence of false-positive transmissions during remote rhythm monitoring with implantable loop recorders


Quadripolar versus bipolar leads in cardiac resynchronization therapy: An analysis of the National Cardiovascular Data Registry


Additional antitachycardia pacing programming strategies further reduce unnecessary implantable cardioverter-defibrillator shocks


Human sub-pulmonary infundibulum has an endocardial network of specialized conducting cardiomyocytes


Redefining the electroanatomy of the cardiac conduction system


The electrocardiogram in the diagnosis and management of patients with hypertrophic cardiomyopathy


Left atrial appendage closure device implantation in patients at very high risk for stroke


When bigger is better: Novel use of a 27 F leadless pacemaker delivery sheath for femoral lead extractions


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Erstellt von Prof. Dr. med. Arash Arya.